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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
BRUCEINE-A IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-A IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-B IC50=0.023-0.5 uM *
BRUCEINE-B IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-B IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C IC50=0.009 uM *
BRUCEINE-C IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=5 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-D IC50=0.037-0.5 uM *
BRUSATOL IC50=0.006 uM *
CARYOPHYLLENE-16-ALPHA-OXIDE IC50=345 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CARYOPHYLLENE-ALPHA-OXIDE EC50=>3-100 uM *
CASTICIN IC50=24 uM *
CASTICIN (Synergic w artemisinin) *
CEDRELONE IC50=0.77 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
CEDRONIN IC50=0.23-0.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CELASTROL IC50=0.181-0.254 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CEPHAELINE IC50=0.011-0.027 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CHAPARRINONE IC50=0.037 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Abelmoschus esculentus Okra 2 70
Abelmoschus moschatus Ambrette; Musk Okra; Tropical Jewel Hibiscus; Muskmallow 1 0
Abutilon theophrasti Velvet Leaf; Butterprint; Indian-Mallow; Abutilon-Hemp 1 0
Acacia catechu Black Cutch; Catechu 2 0
Acacia decurrens Green Wattle 1 0
Acacia farnesiana Cassie; Huisache; Sweet Acacia; Opopanax; Popinac 2 0
Acacia nilotica Babul 3 0
Acacia senegal Gum Arabic; Gum Arabic Tree; Kher; Senegal Gum; Sudan Gum Arabic 1 0
Achillea millefolium Yarrow; Milfoil 7 13, 244
Achyranthes aspera Chaff Flower 1 0
Achyranthes bidentata Chaff Flower 1 0
Acinos suaveolens 1 430
Acrotrema arnottianum 1 5, 300
Acrotrema uniflorum 1 2, 400
Actinidia chinensis Kiwi 1 0
Adansonia digitata 1 0
Adiantum capillus-veneris Maidenhair Fern 1 0
Adonis vernalis Spring Adonis 1 0
Aegle marmelos Bael de India; Bael fruit 1 0
Aesculus hippocastanum Horse Chestnut 2 0