An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. Antimalarial

Antimalarial

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
AJUGARIN-I IC50=23 uM *
AKAGERINE IC50=7 mg/ml Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
AKUAMMIDINE IC50=0.08-0.9 ug/ml Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
AKUAMMIGINE *
AKUAMMINE (1/500th chloroquine) 1 mg/kg Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
ALPHA-CYPERONE 5.5 ug/ml *
ALPHA-CYPERONE IC50=5.5 ug/ml *
ALPHA-PEROXYACHIFOLIDE IC50=1 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPHA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPHA-YOHIMBINE IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALPINUMISOFLAVONE IC50=24.6 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
ALSTOMACROLINE IC50=1.1-10.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTOMACROPHYLLINE IC50=1.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTONERINE IC50=9.7-46.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTONERINE IC50=46.3 uM *
ALSTOPHYLLINE IC50=12.7-82.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ALSTOUMERINE IC50=13.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-A IC50=15.9->23.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-B IC50=9->23.7 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBERTSONINE-C IC50=4.5-10.1 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Lycoris squamigera Magic Lily; Resurrection Lily 1 0
Lythrum salicaria Purple Loosestrife 1 0
Machaerocereus gummosus 1 4, 000
Macleaya cordata Plume Poppy 1 0
Maclura pomifera Osage-Orange; Hedge Apple 4 7, 928
Madhuca microphylla 1 930
Madhuca nerifolia 1 560
Magnolia denudata Hsin-I; Xin-Yi 3 0
Magnolia kobus Hsin-I; Xin-Yi 2 1, 000
Magnolia officinalis Chinese Magnolia; Hou Pu; Magnolia-Bark 1 0
Mahonia aquifolium Oregon Grape; Blue Barberry; Holly Barberry; Holly Mahonia; Mountain Grape 8 195
Mahonia bealei 1 5, 000
Mahonia fargesii 3 0
Mahonia fortunei 2 0
Mahonia gracilipes 4 0
Mahonia japonica Japanese Ashberry; Hiiragi-Nanten 4 0
Mahonia nervosa Oregon Barberry; Oregon Grape-Holly; Oregon Grape; Water Holly 1 0
Mahonia philipinensis 2 0
Mahonia repens Creeping Barberry; Oregon Barberry; Oregon Grape-Holly; Oregon Grape 6 11, 588
Mahonia siamensis 2 4, 600