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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
BRUCEINE-A IC50=0.021-0.5 uM *
BRUCEINE-A IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-B IC50=11 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-B IC50=0.023-0.5 uM *
BRUCEINE-B IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=0.005-0.011 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=0.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BRUCEINE-C IC50=5 ng/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
BRUCEINE-C IC50=0.009 uM *
BRUCEINE-D IC50=0.037-0.5 uM *
BRUSATOL IC50=0.006 uM *
CARYOPHYLLENE-16-ALPHA-OXIDE IC50=345 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CARYOPHYLLENE-ALPHA-OXIDE EC50=>3-100 uM *
CASTICIN IC50=24 uM *
CASTICIN (Synergic w artemisinin) *
CEDRELONE IC50=0.77 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
CEDRONIN IC50=0.23-0.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CELASTROL IC50=0.181-0.254 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CEPHAELINE IC50=0.011-0.027 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CHAPARRINONE IC50=0.037 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Inonotus obliquus 1 0
Inula helenium Elecampane 1 0
Ipomoea batatas Sweet Potato 1 0
Iris missouriensis 1 0
Isatis tinctoria Dyer's Woad 1 0
Jacaranda caucana 1 110
Jasminum officinale Jasmine; Poet's Jessamine 1 0
Jasminum sambac 1 100
Jateorhiza palmata Calumba Root 2 20, 000
Juglans nigra Black Walnut 3 35
Juglans regia English Walnut 4 2, 915
Juniperus communis Common Juniper; Juniper 8 688
Jussiaea suffruticosa 1 0
Kalanchoe pinnata Air Plant; Siempre Viva 1 0
Kalanchoe spathulata Beach Bells 1 0
Kalmia latifolia Mountain Laurel; Calico Bush; Spoonwood 1 81, 000
Kayea stylosa 1 100
Lactuca sativa Lettuce 1 0
Lagerstroemia indica Crape Myrtle 1 0
Lantana camara Lantana; Wild Sage 1 0