Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
ANCISTROBERTSONINE-D	IC50=4.8 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROBREVINE	IC50=5-25 ug/ml	Duke, 1992 *
ANCISTROBREVINE-B	IC50=2-4.7 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROCLADINE	IC50=5-25 ug/ml	Duke, 1992 *
ANCISTROHEYNINE-A	IC50=2.1 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-A	IC50=0.14-0.19 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-B	IC50=0.21-0.54 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANCISTROLIKOKINE-C	IC50=0.62-0.92 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANHYDROLYCORINE	IC50=6.1-6.4 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ANNONACIN	IC50=1.3-1.5 ppm	Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ANOLIGNAN	IC50=20 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
APIOLE	not available	Duke, 1992 *
ARBORININE	IC50=8.5 ug/ml	Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986.
AROMOLINE	IC50=0.67 ug/ml (ca 1/5 chloroquine)	Duke, 1992 *
ARTARINE	not available	Duke, 1992 *
ARTEANNUIN	not available	Duke, 1992 *
ARTEINCULTON	IC50=7.5 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
ARTEMETHER	not available	Merck 11th Edition
ARTEMETIN	(Synergic w artemisinin) IC50=26 uM	Duke, 1992 *
ARTEMISINE	not available	Duke, 1992 *

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Spinacia oleracea	Spinach	2	189
Spondianthus preussii	not available	1	12, 000
Stellaria media	Chickweed; Common Chickweed	1	0
Stemonoporus affinis	not available	1	0
Stemonoporus canaliculatus	not available	1	0
Stemonoporus cordifolius	not available	1	0
Stemonoporus oblongifolius	not available	1	0
Stemonoporus petiolaris	not available	1	0
Stemonoporus reticulatus	not available	1	0
Stephania glabra	Indian Tape-Vine	4	0
Stephania japonica	Japanese Tape-Vine	2	0
Stephania tetrandra	Stephania	1	0
Stevia rebaudiana	Ca-A-E; Sweet Leaf of Paraguay; Stevia	5	237
Strychnos nux-vomica	Nux-Vomica; Stychnine	3	1, 940
Sweetia panamensis	Billy Webb; Cascara Amarga	1	0
Swertia chirata	Chirata; Chiretta	2	0
Symplocos racemosa	not available	1	0
Syncarpia glomulifera	not available	1	12, 000
Syncarpia laurifolia	not available	1	12, 000
Syringa vulgaris	Lilac	2	0