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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
FEBRIFUGINE Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
GALIPININE IC50=0.9 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GALLAGIC-ACID IC50=10.6-10.9 ug *
GAMMA-DICHROINE 100 x quinine Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
GEDUNIN IC50=0.3-1 uM *
GEDUNIN IC50=50 ug/ml *
GEDUNIN IC50=0.7-8.5 ug/ml *
GENTIOPICRIN Merck 11th Edition
GILLETINE IC50=1.1 ug/ml (ca 1/8 x chloroquine) *
GLAUCARUBIN *
GLAUCARUBINONE ED=0.006 ug/ml Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
GLINOSIDE-A IC50=30-42 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GLYCOBISMINE-A (= chloroquine) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
GLYCOCITRINE-I (= chloroquine) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
GONIOTHALAMICIN IC50=1.1-1.6 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
GOSSYPOL IC50=10 uM *
GUTOLACTONE IC50=0.004 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HARMALINE UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp.
HARMINE UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp.
HEPTAPHYLLINE IC50=3-6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Digitalis purpurea Purple Foxglove 1 0
Dillenia anhamanica 1 5, 000
Dillenia aurea 1 7, 200
Dillenia bracteata 1 5, 800
Dillenia indica 1 49, 900
Dillenia pentagyna 1 9, 800
Dillenia retusa 1 35, 400
Dillenia scabrella 1 5, 750
Dionaea muscipula Venus' Fly Trap 1 4, 100
Diospyros abyssinica 1 0
Diospyros argentea 1 0
Diospyros buxifolia 1 0
Diospyros canaliculata 1 0
Diospyros celebica 1 268.6000061035156
Diospyros chevalieri 1 0
Diospyros cinnabarina 1 80
Diospyros consolatae 1 2, 960
Diospyros crassiflora 1 0
Diospyros dendo 1 30
Diospyros derra 1 0