Biological Activity Antimalarial | Dr. Duke's Phytochemical and Ethnobotanical Databases

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name	Dosage	Reference
FEBRIFUGINE	IC50=0.001-0.07 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GALIPININE	IC50=0.9 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GALLAGIC-ACID	IC50=10.6-10.9 ug	Duke, 1992 *
GAMMA-DICHROINE	100 x quinine	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
GEDUNIN	IC50=0.3-1 uM	Duke, 1992 *
GEDUNIN	IC50=50 ug/ml	Duke, 1992 *
GEDUNIN	IC50=0.7-8.5 ug/ml	Duke, 1992 *
GENTIOPICRIN	not available	Merck 11th Edition
GILLETINE	IC50=1.1 ug/ml (ca 1/8 x chloroquine)	Duke, 1992 *
GLAUCARUBIN	not available	Duke, 1992 *
GLAUCARUBINONE	ED=0.006 ug/ml	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
GLINOSIDE-A	IC50=30-42 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
GLYCOBISMINE-A	(= chloroquine)	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
GLYCOCITRINE-I	(= chloroquine)	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
GONIOTHALAMICIN	IC50=1.1-1.6 ppm	Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
GOSSYPOL	IC50=10 uM	Duke, 1992 *
GUTOLACTONE	IC50=0.004 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
HARMALINE	not available	UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp.
HARMINE	not available	UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp.
HEPTAPHYLLINE	IC50=3-6 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.

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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name	Common Name	Chemical Count	Total Parts Per Million
Echinacea spp	Coneflower; Echinacea	3	24
Echinops echinatus	not available	1	0
Echinops niveus	not available	1	0
Ehretia laevis	not available	1	150
Elaeagnus angustifolia	Russian Olive; Silver Berry	4	4, 280
Elaeagnus pungens	Thorny Silver Berry	3	0
Elettaria cardamomum	Cardamom	3	0
Eleutherococcus senticosus	Eleuthero Ginseng; Siberian Ginseng; Spiny Ginseng; Wu jia; Ci wu jia (Pinyin)	3	728.0000019073486
Elsholtzia cristata	Furan Chemotype	1	55
Elsholtzia pilosa	Hairy Mint Shrub	2	16
Elsholtzia polystachya	Bush Mint	3	59.20000019669533
Enterolobium cyclocarpum	not available	1	60
Ephedra gerardiana	Pakistani Ephedra	1	0
Ephedra sinica	Ma Huang; Chinese Ephedra	1	0
Epilobium rosmarinifolium	not available	1	0
Equisetum arvense	Field Horsetail; Horsetail	1	0
Eriobotrya japonica	Loquat	4	11, 455.599975585938
Erythrospermum zeylanicum	not available	1	110
Erythroxylum coca	Coca	1	5, 000
Erythroxylum novogranatense	Coca	1	5, 000