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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. Silybum marianum

Silybum marianum (Asteraceae)

Common Names
Milk Thistle; Lady's Thistle
How this plant is used
Generally Recognized as Safe
View the list of ubiquitous chemicals
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List of plant chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Activity Count Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
(+)-TAXIFOLIN 0 Fruit *
(-)-SILANDRIN 0 Fruit *
1-2-EPOXY-TRIDEC-3-ENE-5-7-9-11-TETRAYNE 0 Root 0.2 *
2,3-DEHYDROSILYCHRISTIN 0 Plant J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
2,3-DEHYDROSILYCHRISTIN 0 Seed *
2,3-DEHYDROSILYMARIN 0 Plant J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
2,3-DEHYDROSILYMARIN 0 Seed *
3-DEOXYSILYCHRISTIN 1 Fruit *
3-DEOXYSILYCHRISTIN 1 Plant *
3-DEOXYSILYCHRISTIN 1 Seed *
3-DEOXYSILYDIANIN 0 Seed Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
4'-5-7-TRIHYDROXY-3'-5'-DIMETHOXY-FLAVANONE 0 Fruit *
4'-5-7-TRIHYDROXY-3'-5'-DIMETHOXY-FLAVANONE 0 Seed *
5,7-DIHYDROXYCHROMONE 4 Plant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ALUMINUM 5 Leaf 59.0 267.0 -0.49 *
ALUMINUM 5 Plant 267.0 -0.23 Pedersen, M. 1987. Nutritional Herbology. Pederson Publishing. Bountiful, Utah. 377 pp.
APIGENIN 101 Fruit *
APIGENIN 101 Seed *
APIGENIN-7-O-BETA-D-(2''-O-ALPHA-L-RHAMNOSYL)-GALACTURONIDE 0 Flower *
APIGENIN-7-O-BETA-D-GLUCURONIDE-6''-ETHYL-ESTER 0 Flower *
View the list of ubiquitous chemicals
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List of plant activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Chemical Count Reference
Gastroprotective 1 *
Gastrostimulant 1 Martindale's 28th
Glucosyl-Transferase-Inhibitor 1 *
Glutathionergic 1 *
Glutathionigenic 1 *
Gonadotrophic 1 Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hemolytic 1 Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Hemostat 1 Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 1 Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective 13 *
Hepatotoxic 1 *
Herbicide 2 Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
HIF-1alpha-Inhibitor 1 *
Histaminic 1 Martindale's 29th
HIV-RT-Inhibitor 2 Garcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991.
Hyaluronidase-Inhibitor 2 *
Hypercholesterolemic 2 Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Hyperglycemic 1 Merck 11th Edition
Hypertensive 2 Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Hypocholesterolemic 11 Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.