An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Plant Frangula purshiana (Rhamnaceae)

Common Names
Cascara Sagrada; Cascara Buckthorn
How this plant is used
Medicinal
View the list of ubiquitous chemicals
List of plant chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Activity Count Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
1,6,8-TRIHYDROXY-3-METHYL-9-GLUCOSYL-ANTHRAQUINONE 0 Plant not available not available not available Duke, 1992 *
10-HYDROXYALOIN-A 0 Bark not available not available not available Duke, 1992 *
10-HYDROXYALOIN-B 0 Bark not available not available not available Duke, 1992 *
11-DEOXYBARBALOIN 0 Bark not available not available not available Duke, 1992 *
ALOE-EMODIN 24 Bark not available not available not available Duke, 1992 *
ALOE-EMODIN 24 Tissue Culture not available not available not available Duke, 1992 *
ALOE-EMODIN-8-MONO-BETA-GLUCOSIDE 0 Bark not available not available not available Duke, 1992 *
ALOE-EMODIN-8-O-BETA-D-GLUCOSIDE 0 Bark not available not available not available Duke, 1992 *
ALOE-EMODIN-DIMER 0 Bark not available 1300.0 not available Duke, 1992 *
ALOIN 12 Plant not available not available not available Duke, 1992 *
ALUMINUM 5 Bark 27.0 99.0 -0.42 Duke, 1992 *
ANTHRANOL 0 Bark not available not available not available Mary, N. Y., Christensen, B. V., Beal, J. L. 1956. A Paper Chromatographic Study of Aloe, Aloin and Cascara sagrada. J. Amer. Pharm. Ass. Sci. Ed., 45: 229-232.
ANTHRAQUINONES 6 Bark 60000.0 100000.0 1.00 Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
ASCORBIC-ACID 112 Bark not available 0.0 -1.01 Duke, 1992 *
ASH 0 Bark 18559.0 67000.0 -0.34 Duke, 1992 *
BARBALOIN 6 Bark not available not available not available Duke, 1992 *
BETA-CAROTENE 53 Bark 13.0 46.0 2.14 Duke, 1992 *
BICASCAROSIDE-AA 0 Bark not available not available not available Duke, 1992 *
BICASCAROSIDE-AB 0 Bark not available not available not available Duke, 1992 *
BICASCAROSIDE-AC 0 Bark not available not available not available Duke, 1992 *
View the list of ubiquitous chemicals
List of plant activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Chemical Count Reference
Hypertensive 1 Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Hypocholesterolemic 7 Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Hypoglycemic 4 Duke, 1992 *
Hypolipidemic 2 Duke, 1992 *
Hypotensive 7 Duke, 1992 *
Hypothermic 1 Pakistan Encyclopedia Planta Medica. 1986.
Hypouricemic 1 Duke, 1992 *
Immunomodulator 6 Economic & Medicinal Plant Research, 6: 189.
Immunostimulant 7 Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Immunosuppressant 3 Duke, 1992 *
iNOS-Inhibitor 1 Duke, 1992 *
Insectifuge 2 Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insulinogenic 3 Duke, 1992 *
Interferon-Synergist 1 Duke, 1992 *
Interferonogenic 1 Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Keratitigenic 1 Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill.
Laxative 7 Duke, 1992 *
Laxative? 1 Lawrence Review of Natural Products, Sep-91.
Leptingenic 1 Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000.
Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Leucocytogenic 1 Duke, 1992 *