Sideritis scardica | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Balkan Sideritis

How used

Medicinal

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Activities: 191

Chemicals w/Activities: 20

All Chemicals: 29

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	1-NONEN-3-OL	Shoot	--	110.0	2.00	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
0	9-EICOSINE	Shoot	--	275.0	--	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
0	ALPHA-PINENE-3-OL	Shoot	--	65.0	--	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
23	ALPHA-TERPINEOL	Shoot	--	70.0	-0.21	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
ACE-Inhibitor 100 ug/ml (weak activity) * Aldose-Reductase-Inhibitor 100 ug/ml Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101. Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. Antiacne * Antibacterial MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY. Anticariogenic MIC=800-1,600 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antiinflammatory * Antiproliferant * Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cicatrizant ED50=240 ug/g mus * FLavor FEMA 5-40 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Insecticide 1.29 uM/fly * Interleukin-6-Inhibitor * Mosquitofuge > Deet * Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Termiticide IC100=5 mg/g * Transdermal * Vulnerary ED50=240 ug/g mus *
36	ANETHOLE	Shoot	--	80.0	--	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allergenic * Antibacterial MBC=200 ug/ml * Antigenotoxic 40-400 mg/kg orl mus * Antihepatotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * AntiNF-kB * Antioxidant * Antiradicular * Antisalmonella MIC=200 ug/ml * Antiseptic 200 ug/ml * Antispasmodic * AntiTNF * Antitumor * Antiyeast * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide * Carminative Merck 11th Edition Dermatitigenic * Digestive Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp. Estrogenic Australian J. Med Herbalism, 7: 29. Expectorant Martindale's 29th Fungicide Wolf, R.B. Effects Of p-Methoxycinnamaldehyde From Star Anise And Related Cinnamic Acid Derivatives On Velvetleaf Germination. Journal of Natural Products, 49(1): 156-158, 1986. Gastrostimulant * Hepatotoxic 695 mg/kg orl mus/days Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Immunostimulant Economic & Medicinal Plant Research, 1: 124. Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp. Lactagogue * Leucocytogenic Economic & Medicinal Plant Research, 1: 124. Mutagenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Nephroprotective Toxicol Appl. Pharmacol. 1996. Pesticide * Secretogogue Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Secretolytic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Sweetener 13 x sucrose * Sympathomimetic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
17	BENZYL-BENZOATE	Shoot	--	36.0	--	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Acaricide LD50=9.22 ug/sq cm cf DEET at 37.59 ug/sq cm * Allergenic Martindale's 29th Antiasthmatic * Antidysmenorrheic * Antispasmodic * Antitumor ED50=8-15 Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Artemicide LC50=2 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. CNS-Depressant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. CNS-Stimulant Martindale's 29th FLavor FEMA 40-300 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hypotensive Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Insectifuge Martindale's 29th Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Myorelaxant * Pediculicide Martindale's 29th Pesticide * Scabicide Merck 11th Edition
0	BETA-CARYOPHYLLENE	Shoot	--	105.0	-0.20	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
0	BETA-FARNESENE	Shoot	--	49.0	-0.18	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
13	BETA-IONONE	Shoot	--	41.0	-0.48	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allergenic * Antibacterial MIC=200 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticariogenic MIC=100 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antimelanomic IC50=140 uM/l * Antitumor Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cytochrome-P450-Inducer * Fungicide * Hypocholesterolemic Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147. Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. P450-Inducer * Pesticide * Trichomonicide LD100=100 ug/ml *
41	CAMPHOR	Shoot	--	75.0	-0.15	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allelopathic * Analgesic * Anesthetic * Antiacne Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Antidiarrheic 500 ug/ml Wealth of India. Antidysenteric 500 ug/ml Wealth of India. Antiemetic 100-200 mg man orl Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antifeedant IC50=5,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Antifibrositic Martindale's 28th Antineuralgic Martindale's 28th Antipruritic Merck 11th Edition Antiseptic Merck 11th Edition Antispasmodic ED50=0.075 mg/ml Fitoterapia No.59-1984. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. CNS-Stimulant * Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Counterirritant Martindale's 28th Decongestant Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Deliriant Merck 11th Edition Ecbolic * Emetic * Epileptigenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Expectorant Martindale's 29th Fungicide ED50=2.7 mM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Herbicide IC50=3.3-180 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Insect-Repellent * Insectifuge * Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Occuloirritant * P450-2B1-Inhibitor IC50=7.89 uM * Pesticide * Respirainhibitor Merck 11th Edition Respirastimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Rubefacient * Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Transdermal * Verrucolytic Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Vibriocide 500 ug/ml Wealth of India.
19	CARVONE	Shoot	--	20.0	-0.26	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allergenic * Antiacetylcholinesterase IC50=1.4-1.8 mM * Antiproliferative * Antiseptic 1.5 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidistat * Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. CNS-Stimulant * FLavor FEMA 80-3,000 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungistat * Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC Trichomonicide LD100=300 ug/ml * Vermicide *
0	CINEOLE	Shoot	--	27.0	-1.00	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
1	COPAENE	Shoot	--	34.0	1.41	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Carminative *
0	EO	Shoot	--	4350.0	-0.55	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
17	FARNESOL	Shoot	--	80.0	2.11	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allergenic * Antiadenomic * Anticancer (Pancreas) IC50=39 uM * Anticarcinomic (Colon) * Anticarcinomic (Lung) * Antileukemic * Antimelanomic IC50=50 uM/l * Antispasmodic * Apoptotic * FLavor FEMA 0.1-3 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Juvabional Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134. Nematicide MLC=100 ug/ml Shoyakugaku Zasshi, 44: 183. Perfumery Merck 11th Edition Pesticide * Pheromonal * Sedative * Trichomonicide LD100=100 ug/ml *
35	GERANIOL	Shoot	--	245.0	-0.36	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allergenic * Anthelmintic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus. Antibacterial MIC=64 ug/ml * Antibacterial MBC=800 ug/ml * Antibacterial MIC=400 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Anticancer (Pancreas) IC50=265 uM * Anticariogenic MIC=400 ug/ml Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105. Antimelanomic IC50=150 uM/l * Antisalmonella MIC=400 ug/ml * Antiseptic 7 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Antiseptic MIC=64 ug/ml * Antiseptic 400-800 ug/ml * Antispasmodic Buchbauer, G., Jirovetz, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990. Antitubercular MIC=64 ug/ml Antitumor Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147. Antitumor (Pancreas) IC50=265 uM * Ascaricide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide * CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. Embryotoxic * Emetic 3 x ipecac Lawrence Review of Natural Products, Sep-97. Expectorant Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus. FLavor FEMA 1-10 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Fungicide IC93=2 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Herbicide IC100-2,000 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectifuge 50 ppm * Insectiphile Merck 11th Edition Mycobactericide MIC=64 ug/ml * Nematicide MLC=1,000 ug/ml Shoyakugaku Zasshi, 44: 183. Nematicide IC86=100 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Perfumery Merck 11th Edition Pesticide * Sedative * Trichomonicide LD100=300 ug/ml *
2	HUMULENE	Shoot	--	22.0	-0.62	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Antimalarial IC50=86 ug/ml * Antiplasmodial IC50=86 ug/ml *
63	MENTHOL	Shoot	--	370.0	-0.09	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Allergenic Martindale's 29th Analgesic Martindale's 28th Anesthetic 2,000 ppm Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Antiacetylcholinesterase IC50=2.0 mM * Antiaggregant IC50=750 * Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569. Antiasthmatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antibacillus MIC=1.25 mg/ml * Antibacterial MIC=0.625-2.5 * Antibronchitic Martindale's 28th Antidandruff A.L.L. Hunting. Encyclopedia of Shampoo Ingredients. Micelle Press, Cranford NJ. 467 pp. Antiescherichic MIC=1.25 mg/ml * Antihalitosic American Health, 12(4): 17, 1993. Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569. Antiinflammatory Martindale's 28th Antilisteria MIC=0.625 mg/ml * Antineuralgic * Antiodontalgic Martindale's 28th Antipruritic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Antipyretic * Antirheumatic Martindale's 28th Antisalmonella MIC=0.625 mg/ml * Antiseptic 4 x phenol Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176) Antisinusitic Martindale's 28th Antispasmodic ED50=0.01 mg/ml Fitoterapia No.59-1984. Antistaphylococcic MIC=0.625 mg/ml * Antistreptococcic MIC=0.4 mg/ml * Antitartar * Antivaginitic * Antivulvitic * Bradycardic 65 mg/3 x day/woman Martindale's 28th Bronchomucolytic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200. Bronchomucotropic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Bronchorrheic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200. Calcium-Antagonist * Candidicide MIC=0.625 mg/ml * Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Choleretic * Ciliotoxic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. CNS-Depressant * CNS-Stimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Congestant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R. Counterirritant * Decongestant? 11 mg/man Eccles, R., et al. 1989. The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. J. Pharm. Pharmacol. 42: 652-654, 1990. Dermatitigenic * Diaphoretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Enterorelaxant J. Aromatherapy 4: 22. Expectorant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Gastrosedative Merck 11th Edition Irritant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Myorelaxant Martindale's 29th Nematicide MLC=1 mg/ml Shoyakugaku Zasshi, 44: 183. Neurodepressant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Neuropathogenic 40-100 mg/day/rat Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Nociceptive Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Perfumery Merck 11th Edition Pesticide * Refrigerant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994. Rubefacient * Termiticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Transdermal * Vibriocide *
2	MENTHYL-ACETATE	Shoot	--	60.0	1.99	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Antispasmodic ED50=0.105 mg/ml Fitoterapia No.59-1984. Perfumery Merck 11th Edition
10	NEROL	Shoot	--	65.0	-0.28	Menkovic, N., et al. 1991. The Essential Oil of Sideritis scardica. Pl. Med. 57. Suppl. 2. pp. A137-A132.
Antibacterial HerbalGram No. 17. Antihelicobacter * Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Antiulcer * Estrogenic * FLavor FEMA 1-20 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Perfumery Merck 11th Edition Pesticide * Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Trichomonicide ED100=300 ug/ml *

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Sideritis scardica (Lamiaceae)

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