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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. MENTHOL

MENTHOL

Chemical ID
MENTHOL
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=700-3,180 (orl rat) Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994., Merck 11th Edition
LDlo=2,000->9,000 mg/man/? Martindale's 28th
ADI=200 ug/kg
LD50=3,300 mg/kg (orl rat) Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh., Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Allergenic Martindale's 29th
Analgesic Martindale's 28th
Anesthetic 2,000 ppm Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Antiacetylcholinesterase IC50=2.0 mM *
Antiaggregant IC50=750 *
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antiasthmatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Antibacillus MIC=1.25 mg/ml *
Antibacterial MIC=0.625-2.5 *
Antibronchitic Martindale's 28th
Antidandruff A.L.L. Hunting. Encyclopedia of Shampoo Ingredients. Micelle Press, Cranford NJ. 467 pp.
Antiescherichic MIC=1.25 mg/ml *
Antihalitosic American Health, 12(4): 17, 1993.
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Antiinflammatory Martindale's 28th
Antilisteria MIC=0.625 mg/ml *
Antineuralgic *
Antiodontalgic Martindale's 28th
Antipruritic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Antipyretic *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Achillea millefolium Plant *
Acinos suaveolens Shoot 3.0 -0.6 Tumen, G. 1991. The Volatile Constituents of Acinos suaveolens (Sibt. et Smith). G. Don fil. Growing in Turkey. J. Ess. Oil Res. 3:191-2.
Acorus calamus Rhizome Pakistan Encyclopedia Planta Medica. 1986.
Agathosma betulina Leaf Essent. Oil *
Artemisia annua Plant *
Artemisia dracunculus Essential Oil *
Artemisia dracunculus Shoot 50.0 500.0 0.1 *
Brassica oleracea var. capitata l. Leaf *
Brassica oleracea var. capitata l. Plant *
Calamintha nepeta Leaf 1.0 -0.6 Akgul, A., De Pooter, H.L., and De Buyck, L.F. 1991. The Essential Oils of Calamintha nepeta subsp. glandulosa and Ziziphora clinopodioides from Turkey. J. Ess. Oil Res., 3: 7-10.
Calamintha nepeta Plant 290.0 -0.4 J. Ethnopharmacology, 39: 167.
Camellia sinensis Leaf *
Cocos nucifera Fruit Jim Duke's personal files.
Cymbopogon nardus Plant Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Elytrigia repens Plant 15.0 20.0 -0.6 Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elytrigia repens Rhizome 18.0 1.0 Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Eucalyptus citriodora Leaf Essent. Oil *
Glechoma hederacea Plant Chemical Constituents of Oriental Herbs (3 diff. books)
Hedeoma drummondii Plant 10.0 -0.6 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Hedeoma pulegioides Plant 6.0 30.0 -0.6 *