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| Chemical Name Sort descending | Dosage | Reference |
|---|---|---|
| (+)-CORYDALINE | 50 uM (weak activity) | Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459. |
| (+)-GLAUCINE | 50 uM | Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459. |
| (-)-DANSHEXINKUN | IC50=0.87 uM | Tezuka, Y., Kasimu, R., Basnet, P., Namba, T., Kadota, S. 1997. Aldose Reductase Inhibitory Constituents of the Root of Salvia miltiorhiza Bunge. Chem Pharm Bull, 45(8): 1306-1311. |
| (-)-EPIGALLOCATECHIN | not available | Duke, 1992 * |
| (-)-EPIGALLOCATECHIN-GALLATE | not available | Duke, 1992 * |
| (-)-STYLOPINE | 50 uM | Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459. |
| (-)-TETRAHYDROCOLUMBAMINE | 50 uM (weak activity) | Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459. |
| 1,2,3,6-TETRA-O-GALLYOL-BETA-D-GLUCOSE | IC50=0.63 uM | Duke, 1992 * |
| 1,3,6-TRIHYDROXY-2,7-DIMETHOXY-XANTHONE | 0.1 uM | Iketani, Y., Mihashi, H., Sato, S., Takeda, H. 1992. Xanthones as Aldose Reductase Inhibitors. Patent, Japan Kokai Tokkyo Koho-04 139,180: 7pp. |
| 1,6,7-TRIHYDROXY-2,3-DIMETHOXY-XANTHONE | not available | Mao, S.L., Liao, S. X., Wu, J. H., Liang, H. Q., Chen, H. S., Zhang, C. K. 1996. Studies on Chemical Constituents of Polygala arillat a Buch-Ham. Yao Hsueh Hsueh Pao, 31(2): 118-121. |
| 1-HYDROXY-3,6,7-TRIMETHOXY-XANTHONE | 0.1 uM | Iketani, Y., Mihashi, H., Sato, S., Takeda, H. 1992. Aldose Reductase Inhibitors Containing Natural Xanthones and Their Synthetic Analogs. Patent, Japan Kokai Tokkyo Koho-04 139,179, 12pp. |
| 1-METHOXY-2,3-METHYLENEDIOXY-XANTHONE | not available | Mao, S.L., Liao, S. X., Wu, J. H., Liang, H. Q., Chen, H. S., Zhang, C. K. 1996. Studies on Chemical Constituents of Polygala arillat a Buch-Ham. Yao Hsueh Hsueh Pao, 31(2): 118-121. |
| 13',II8-BIAPIGENIN | IC25=10 uM | Shimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888. |
| 2'O-ACETYLACETOSIDE | IC50=0.19 uM | Duke, 1992 * |
| 2-METHYL-5-(PENTADEC-CIS-8-ENYL)-RESORCINOL | IC50=300.7 uM | Toyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254. |
| 2-METHYL-5-(PENTADECA-CIS-8-CIS-11-DIENYL)-RESORCINOL | IC50=118 uM | Toyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254. |
| 2-PHENYL-ETHYL-O-BETA-D-XYLOPYRANOSYL-(1,6)-BETA-D-GLUCOSIDE | not available | Nishimura, H., Morota, T., Yamaguchi, T., Chin, M. 1990. Extraction of Phenethyl Alcohol Derivatives as Aldose Reductase Inhibitors for Treatment of Diabetes-Related Diseases. Patent, Japan Kokai Tokkyo Koho-02 36,189. 13pp. |
| 28-HYDROXY-FRIEDELANE-1,3-DIONE | IC50=12 ug/ml | Chavez, H., Estevez-Braun, A., Ravelo, A. G., Gonzalez, A. G. 1998. Friedelane Triterpenoids from Maytenus macrocarpa. J. Nat. Prod., 61(1): 82-85. |
| 3',4',5,6,7-PENTAACETOXY-8-METHOXY-FLAVONE | 10 uM (strong activity) | Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
| 3',4',6-TRIHYDROXY-5,7,8-TRIMETHOXY-FLAVONE | 10 uM (strong activity) | Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822. |
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| Plant Name Sort descending | Common Name | Chemical Count | Total Parts Per Million |
|---|---|---|---|
| Abelmoschus esculentus | Okra | 4 | 4, 750 |
| Abelmoschus moschatus | Ambrette; Musk Okra; Tropical Jewel Hibiscus; Muskmallow | 2 | 0 |
| Abies alba | Silver-Fir | 3 | 45 |
| Abutilon theophrasti | Velvet Leaf; Butterprint; Indian-Mallow; Abutilon-Hemp | 2 | 0 |
| Acacia catechu | Black Cutch; Catechu | 6 | 0 |
| Acacia decurrens | Green Wattle | 2 | 0 |
| Acacia farnesiana | Cassie; Huisache; Sweet Acacia; Opopanax; Popinac | 9 | 13, 180 |
| Acacia melanoxylon | Blackwood | 1 | 0 |
| Acacia nilotica | Babul | 7 | 0 |
| Acacia senegal | Gum Arabic; Gum Arabic Tree; Kher; Senegal Gum; Sudan Gum Arabic | 3 | 0 |
| Acacia tortilis | Umbrella Thorn | 1 | 0 |
| Acalypha indica | Cancer Herb; Indian Acalypha; Copperleaf; Indian Nettle; Three-Seeded-Mercury | 2 | 37, 700 |
| Achillea millefolium | Yarrow; Milfoil | 19 | 11, 060 |
| Acinos alpinus | Te de Sierra Nevada | 4 | 20 |
| Acinos suaveolens | not available | 11 | 2, 575.7000002861023 |
| Aconitum napellus | European Aconite; Monkshood; Aconite; Bear's-Foot; Blue Rocket; Friar's Cap; Garden Monkshood; Garden Wolfsbane; Helmet Flower; Queen's Fettle; Soldier's Cap; Turk's Cap | 2 | 0 |
| Acorus calamus | Sweetflag; Calamus; Flagroot; Myrtle Flag; Sweet Calamus; Sweetroot | 6 | 15, 300 |
| Actaea cimicifuga | Sheng ma; Bugbane; Foetid Bugbane | 2 | 0 |
| Actaea dahurica | Sheng ma; Xing an sheng ma | 1 | 0 |
| Actaea racemosa | Black Cohosh; Black Snakeroot | 3 | 42 |