Lactuca scariola | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Prickly Lettuce

How used

GRAS

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Activities: 194

Chemicals w/Activities: 19

All Chemicals: 26

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List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
5	8-DEOXYLACTUCIN	Plant	--	--	--	*
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Bitter 1.1 ppm * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide *
32	ALPHA-TOCOPHEROL	Seed	--	--	--	*
Antialzheimeran * Antianginal * Antiarthritic * Antiasthmatic * Antiatherosclerotic Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Anticancer * Anticataract * Anticonvulsant Synergen * Antidementia * Antidiabetic Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Antiinfarctal Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Antiinfertility * Antiischemic * Antimaculitic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuropathic * Antioxidant 5 x quercetin * Antioxidant IC34=10 uM * Antiparkinsonian * Antiradicular 5 x quercetin * Antiretinotic * Antirheumatic * Antistroke * Antitumor * Antitumor (Bladder) * Antitumor (Prostate) * Antitumor (Stomach) * Antitumor-Promoter * Cancer-Preventive * Cardioprotective * Circulotonic * Immunomodulator *
0	ARACHIDIC-ACID	Seed	--	1091.0	-0.55	*
9	BETA-AMYRIN	Plant	--	--	--	*
Analgesic * Antiedemic IC27=40 mg/kg ipr rat * Antiinflammatory * Antinociceptive * Antiulcer * Gastroprotective * Hepatoprotective * Larvicide * Mosquitocide *
0	BETA-LACTUCEROL	Latex Exudate	--	--	--	*
47	BETA-SITOSTEROL	Seed	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	CAOUTCHOUC	Latex Exudate	--	--	--	*
1	CAPROIC-ACID	Seed	--	7392.0	1.32	*
Irritant *
23	CITRIC-ACID	Latex Exudate	--	--	--	*
Allergenic * Alpha-Amylase-Inhibitor * Antiaphthic 20,000 ppm Martindale's 28th Antiatherosclerotic * Antibacterial * Anticalculic * Anticoagulant Merck 11th Edition Antileishmanic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Disinfectant Martindale's 29th FLavor FEMA 370-4,400 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hemostat * Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Laxative? Lawrence Review of Natural Products, Sep-91. Litholytic Martindale's 29th Mycobactericide * Odontolytic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Refrigerant Martindale's 28th
0	FAT	Seed	--	352000.0	0.46	*
0	GAMMA-LACTUCEROL	Latex Exudate	--	--	--	*
0	GERMANICOL	Plant	--	--	--	*
27	HYOSCYAMINE	Latex Exudate	--	--	--	*
Analgesic Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp. Anticholinergic 150-300 ug 4 x/day/man Martindale's 29th Antidote (Anticholinesterase) Martindale's 29th Antiemetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiherpetic * Antimeasles * Antimuscarinic Martindale's 29th Antineuralgic * Antiparkinsonian Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antipolio * Antisialogogue Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antispasmodic * Antiulcer Martindale's 29th Antivertigo * Antivinous * Antiviral * Bronchodilator * Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Cardiotonic * CNS-Depressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. CNS-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Mydriatic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Photophobigenic * Psychoactive Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp. Sedative * Toxic *
19	INULIN	Root	--	--	--	*
Alcohol-Dehydrogenase-Inhibitor (diagnostic)=50 mg/kg/ivn/man Martindale's 29th Anticolitic? * Antidiabetic * Antidiarrheic * Antiobesity? * Antiosteoporotic? * Bifidogenic * Chemopreventive (Breast Cancer) * Chemopreventive (Colon Cancer) * Expectorant Pedersen, M. 1987. Nutritional Herbology. Pederson Publishing. Bountiful, Utah. 377 pp. Gastrostimulant * Hypocholesterolemic * Hypoglycemic * Immunostimulant * Laxative * Lipolytic * Prebiotic * Probiotic * Probiotigenic *
6	LACTUCIN	Latex Exudate	--	--	--	*
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Bitter 1.7 ppm * CNS-Depressant * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Sedative Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Tonic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
4	LACTUCOPICRIN	Plant	--	--	--	*
Bitter 0.5 ppm * CNS-Depressant * Hypoglycemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Sedative *
27	LINOLEIC-ACID	Seed	165616.0	204160.0	0.83	*
5-Alpha-Reductase-Inhibitor * Antiacne * Antialopecic * Antianaphylactic Economic & Medicinal Plant Research, 6: 189. Antiandrogenic * Antiarteriosclerotic * Antiarthritic Economic & Medicinal Plant Research, 6: 189. Anticoronary Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antieczemic Economic & Medicinal Plant Research, 6: 189. Antifibrinolytic Economic & Medicinal Plant Research, 1: 53. Antigranular * Antihistaminic Economic & Medicinal Plant Research, 6: 189. Antiinflammatory IC50=31 uM * Antileukotriene-D4 IC50=31 uM * Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiMS Economic & Medicinal Plant Research, 6: 189. Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic Science News, 146: 421. Comedolytic * Hepatoprotective * Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Immunomodulator Economic & Medicinal Plant Research, 6: 189. Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Metastatic Science News, 146: 421. Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Propecic *
15	MALIC-ACID	Latex Exudate	--	--	--	*
Antiatherosclerotic * Antibacterial * Antifibromyalgic 300 mg 3x/day * Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Bacteristat * Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Hemopoietic * Laxative? Lawrence Review of Natural Products, Sep-91. Mycobactericide * Pesticide * Sialogogue Martindale's 29th
18	MANNITOL	Latex Exudate	--	--	--	*
Allergenic Martindale's 29th Analgesic * Anthelmintic ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Antiglaucomic Martindale's 28th Antiinflammatory ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Antimutagenic * Antinephritic Martindale's 29th Antioxidant Jim Duke's personal files. Antiradicular * AntiReye's Martindale's 29th Antispasmodic ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes. Diuretic Merck 11th Edition Emetic Martindale's 28th Flatugenic Martindale's 29th Laxative * Nephrotoxic Martindale's 29th Pesticide * Sweetener Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
18	OLEIC-ACID	Seed	95040.0	130170.0	0.09	*
5-Alpha-Reductase-Inhibitor * Allergenic * Alpha-Reductase-Inhibitor * Anemiagenic * Antialopecic * Antiandrogenic * Antiinflammatory IC50=21 uM * Antileukotriene-D4 IC50=21 uM * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Choleretic 5 ml/man * Dermatitigenic * FLavor FEMA 1-30 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hypocholesterolemic Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.) Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Irritant Merck 11th Edition Percutaneostimulant Seki, T., Toeda, C., Kawaguchi, T., Juni, K., Sugibayashi, K., and Morimoto, Y. 1990. Enhanced Transdermal Delivery of Zidovudine in Rats and Human Skin. Chem. Pharm. Bull. 38(11): 3086-3089, 1990. Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Propecic *

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Lactuca scariola (Asteraceae)

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