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Chemical CURCUMIN

Chemical ID
CURCUMIN
Ubiquitous
No
List of known dosages
Dosage Reference
LDlo=>2,000 mg/kg (orl mus) Martindale's 28th
ADI=100 ug/kg Martindale's 29th
TD=>5,000 mg/kg (orl rat)
LDlo=>1,800 mg/kg (orl rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending Dosage Reference
Immunostimulant 40 mg/kg/5 wk orl rat Duke, 1992 *
Lipase-Inducer not available Duke, 1992 *
Litholytic 0.5% diet Duke, 1992 *
Maltase-Promoter not available Duke, 1992 *
MDR-Inhibitor 1-55 uM Duke, 1992 *
Metal-Chelator not available McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
MMP-9-Inhibitor 10 uM Duke, 1992 *
Mucogenic 100 uM Duke, 1992 *
Nematicide not available Duke, 1992 *
Neuroprotective 80 mg/kg igs rat Duke, 1992 *
NF-kB-Inhibitor not available Duke, 1992 *
NO-Inhibitor not available Duke, 1992 *
NO-Scavenger not available Duke, 1992 *
Ornithine-Decarboxylase-Inhibitor ED=~150 mg/kg Duke, 1992 *
P450-Inhibitor IC50=2-14 ug/ml Duke, 1992 *
Pesticide not available Duke, 1992 *
PGE2-Inhibitor IC42=3 uM Duke, 1992 *
Phototoxic not available Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Plasmodicide not available Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor 0.2% diet rat Rao, C. V., Rivenson, A., Simi, B., Reddy, B. S. 1995. Chemoprevention of Colon Carcinogenesis by Dietary Curcumin, a Naturally Occurring Plant Phenolic Compound. Cancer Research, 55(2): 259-266.
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