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Chemical ID
COUMARIN
Ubiquitous
No
| Dosage | Reference |
|---|---|
| LD50=202 (orl gpg) | Merck 11th Edition |
| LD50=293 (orl rat) | CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses, Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. |
| LD50=680 (orl rat) | Merck 11th Edition |
| LD50=720 (orl rat) |
| Activity | Dosage | Reference |
|---|---|---|
| Aldose-Reductase-Inhibitor | 10 ug/ml cow (weak activity, 11% inhibition) | Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 |
| Allelochemic | IC100=2 mM | Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. |
| Analgesic | not available | Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. |
| Anesthetic | not available | Duke, 1992 * |
| Antiaggregant | not available | Duke, 1992 * |
| Antiandrogenic | not available | Planta Medica, 56(6): 671, 1990. |
| Antibrucellosic | not available | Gawron, A., Gorski*, G., Glowniak**, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990. |
| Anticancer (Kidney) | 400-7,000 mg/day | Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. |
| Anticancer (Prostate) | 400-7,000 mg/day | Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. |
| Antidiuretic | not available | Duke, 1992 * |
| Antiedemic | not available | Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. |
| Antiesherichic | not available | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
| Antiinflammatory | not available | Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990. |
| Antilymphedemic | not available | Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. |
| Antimelanomic | 50 mg/day | Duke, 1992 * |
| Antimetastatic | 50 mg/man/day | Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. |
| Antimitotic | not available | Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7. |
| Antimononuccleotic | not available | Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. |
| Antimutagenic | not available | Economic & Medicinal Plant Research, 6: 235. |
| Antimycoplasmotic | not available | Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. |
| Plant Name | Plant Part | Low Parts Per Million | High Parts Per Million | Standard Deviation | Reference |
|---|---|---|---|---|---|
| Acacia farnesiana | Flower | not available | not available | not available | Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. |
| Acacia farnesiana | Plant | not available | not available | not available | Pakistan Encyclopedia Planta Medica. 1986. |
| Ageratum conyzoides | Plant | not available | not available | not available | List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979. |
| Ageratum conyzoides | Shoot | not available | 1040.0 | -1.0 | R. Vera, (1993); Chemical composition of the essential oil Ageratum conyzoides L. (Asteraceae) from Reunion, Flavour Fragr. J., Vol.8, 257-260. |
| Aloe vera | Plant | not available | not available | not available | Pakistan Encyclopedia Planta Medica. 1986. |
| Althaea officinalis | Shoot | not available | not available | not available | Duke, 1992 * |
| Althaea officinalis | Root | not available | not available | not available | Duke, 1992 * |
| Ammi visnaga | Plant | not available | not available | not available | Duke, 1992 * |
| Apium graveolens | Plant | not available | not available | not available | Duke, 1992 * |
| Artemisia annua | Shoot | not available | not available | not available | Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands. |
| Artemisia annua | Plant | not available | not available | not available | Father Nature's Farmacy: The aggregate of all these three-letter citations. |
| Artemisia capillaris | Plant | not available | not available | not available | Duke, 1992 * |
| Artemisia dracunculus | Plant | not available | not available | not available | Duke, 1992 * |
| Artemisia vulgaris | Plant | not available | not available | not available | Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. |
| Astragalus membranaceus | Root | not available | not available | not available | Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. |
| Capparis spinosa | Plant | not available | not available | not available | Duke, 1992 * |
| Cichorium intybus | Plant | not available | not available | not available | Duke, 1992 * |
| Cinnamomum aromaticum | Bark | not available | not available | not available | Duke, 1992 * |
| Cinnamomum verum | Leaf Essent. Oil | not available | not available | not available | Duke, 1992 * |
| Cinnamomum verum | Stem Bark | not available | not available | not available | Duke, 1992 * |