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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. CAFFEINE

CAFFEINE

Chemical ID
CAFFEINE
CAS Registry Number
58082
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=127-1,200 (orl mus) Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006., Merck 11th Edition
LD50=192 (orl rat)
LD50=200 (orl rat)
LD50=224-246 (orl rbt)
LD50=247-355 (orl rat) Merck 11th Edition
LDlo=192 (orl hmn)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antiserotonergic 40 scu rat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antitumor *
Antitumor (Lung) *
Antivaccinia *
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Apoptotic *
Arrhythmigenic 1,500 mg/man *
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic 10-25 orl dog Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiotonic 65-500 orl cat Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Catabolic Abstract (See species file)
cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Choleretic *
CNS-Stimulant 100 orl mus *
CNS-Stimulant 30 orl rat *
Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Diuretic *
Energizer 20-200 mg/man *
Ergotamine-Enhancer Martindale's 29th
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Annona cherimola Seed *
Camellia sinensis Stem *
Camellia sinensis Seed *
Camellia sinensis Pericarp *
Camellia sinensis Anther 0.1 *
Camellia sinensis Leaf 3810.0 93000.0 1.4 *
Camellia sinensis Tissue Culture *
Camellia sinensis Shoot 38100.0 47900.0 *
Camellia sinensis Seed Coat *
Camellia sinensis Flower *
Camellia sinensis Plant *
Citrus limon Flower 50.0 0.2 *
Citrus paradisi Flower 29.0 -1.3 CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
Citrus sinensis Flower 62.0 1.1 Jim Duke's personal files.
Citrus sinensis Leaf 6.0 -0.9 Jim Duke's personal files.
Citrus sinensis Bud 0.3 Jim Duke's personal files.
Coffea arabica Seed 600.0 32000.0 0.3 *
Cola acuminata Seed 10000.0 25000.0 0.0 *
Firmiana simplex Seed *
Genipa americana Seed 22500.0 -0.1 Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.