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Chemical CAFFEINE

Chemical ID

CAFFEINE

CAS Registry Number

58082

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=127-1,200 (orl mus)	Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006., Merck 11th Edition
LD50=192 (orl rat)
LD50=200 (orl rat)
LD50=224-246 (orl rbt)
LD50=247-355 (orl rat)	Merck 11th Edition
LDlo=192 (orl hmn)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Sort descending	Dosage	Reference
Topoisomerase-II-Inhibitor	99 mM	Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Vasodilator	not available	Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.

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