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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Xanthine-Oxidase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
NEPETIN *
OENOTHEIN-B IC50=20 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OENOTHEIN-C IC50=11 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OPC IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OPCS IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
OSTHOL IC10=10 uM *
PEDUNCULAGIN IC50=18 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
PENTA-O-GALLOYL-BETA-D-GLUCOSE IC50=3.3 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
POLYPHENOLS *
PROCYANIDIN IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
PROCYANIDINS IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
PROCYANIDINS IC50=2.4 uM/l *
PUERARIN Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
QUERCETIN IC50=10.6 ug/ml *
QUERCETIN 3.1 uM *
QUERCETIN IC50=>0.4 ug/ml Chem. & Pharm. Bull. 38: 1772.
RABDOSIN IC50=>40 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
RUGOSIN-A IC50=8 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
RUGOSIN-D IC50=3.1 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
TANNIN *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Petiveria alliacea Anamu; Guinea Hen Leaf; Mucura 1 0
Petroselinum crispum Parsley 6 56, 017
Peucedanum ostruthium Masterwort 2 0
Peumus boldus Boldo 1 0
Phaseolus vulgaris Black Bean; Green Bean; Haricot Bean; Garden Bean; String Bean; Dwarf Bean; Field Bean; Flageolet Bean; French Bean; Kidney Bean; Navy Bean; Pop Bean; Popping Bean; Snap Bean; Wax Bean; Haricot Vert; Haricot 5 159.80000162124634
Phoenix dactylifera Date Palm 5 48, 000.17000000179
Phyllanthus amarus 3 11, 486.299987792969
Phyllanthus emblica Emblic; Myrobalan 5 1, 207, 900
Phyllanthus niruri Seed On The Leaf 1 0
Physalis alkekingi Bladderherb; Lantern 1 0
Phytolacca americana Pokeweed 1 0
Pimpinella anisum Anise; Sweet Cumin 5 16, 620
Pinus insularis Khasi Pine 1 100, 000
Pinus kesiya Khasi Pine 1 100, 000
Pinus mugo Dwarf Pine; Swiss Mountain Pine 1 0
Pinus strobus Eastern White Pine; White Pine 1 0
Pinus sylvestris Scotch Pine 6 169, 000
Piper angustifolium Matico 1 0
Piper betel Betel Pepper 1 20, 500
Piper nigrum Black Pepper; Pepper; White Pepper 3 18