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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Pyrogenic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(-)-CATHINONE 16-24 mg/kg ipr rbt Kalix, P. 1980. Hyperthermic Response to (-)-Cathinone, an Alkaloid of Catha edulis (KHAT). J Pharm Pharmacol, 32: 662-663.
ADENOSINE 0.09 mg/kg ivn hmn Conradson, T. B. G., Dixon, C. M. S., Clarke, B., Barnes, P. J. 1987. Cardiovascular Effects of Infused Adenosine in Man: Potentiation by Dipyridamole. Acta Physiol Scand, 129(3): 387-391.
ARACHIDONIC-ACID 100 ug/kg rbt Kandasamy, S. B. 1977. Central Effect of 5,8,11,14-eicosatetraenoic Acid (Arachidonic Acid) on the Temperature in the Conscious Rabbit. Experientia, 33: 1626.
BETA-PHENETHYLAMINE 50 mg/kg ipr mus *
BRUCEANTIN 5.5 mg/sq m body, ivn hmn Garnick, M. B., Blum, R. H., Canellos, G. P., Mayer, R. J., Parker, L., Skarin, A. T., Li, F. P., Henderson, I. C., Frei III, E. 1979. Phase I Trial of Bruceantin. Cancer Treat Rep, 63: 1929-1932.
CAFFEINE 60 mg/day oral hmn Daroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191.
CAFFEINE 13.3 mg/kg ipr rbt Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
CAFFEINE 15 mg/kg ipr cat Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
CAPSAICIN 6 mg scu rat Cabanac, M., Leydier, M. C., Poirier, L. J. 1976. The Effect of Capsaicin on Temperature Regulation of the Rat. Pfluegers Arch, 366: 217.
CARRAGEENAN 10 mg ipr rat Sobanski, H., Krupinska, J., Gryglewski, R. J. 1974. Carrageenin Hyperthermia in Rats. Experientia, 30: 1326.
CELASTRINE *
COCAINE 5 mg/kg ivn mky Wilson, M. C., Bedford, J. A., Buelke, J., Kibbe, A. H. 1976. Acute Pharmacological Activity of Intravenous Cocaine in the Rhesus Monkey. Psychopharmacol Commun, 2: 251.
GINSENOSIDE-RG-1 50 mg/kg ipr mus Takagi, K. 1977. Pharmacological Studies on Ginseng. Korean Ginseng Studies, Il Hwa Co., Ltd., Seoul, South Korea, 1977: 346-357.
GLAUCINE 10 mg/kg igs rat Pinto, L., Borrelli, F., Bombardelli, E., Cristoni, A., Capasso, F. 1998. Anti-Inflammatory, Analgesic and Antipyretic Effects of Glaucine in Rats and Mice. Pharm Pharmacol Commun, 4(10): 502-505.
MAJARINE 0.1 mg/kg ipr mus Park, Y. H., Lee, J. H., Kim, Y. J., Cho, B. H. 1985. The Actions of Majarine on the Central Nervous System. II. The Effect of Dopaminergic and Serotonergic Antagonists on Majarine-Induced Hypothermia in the Mouse. Taehan Yakrihak Chapchi, 21(2): 99-110.
O-METHYL-HYDROXYPTELEFOLINIUM ipr rat Minker, E., Koltai, M., Blazso, G., Szendrei, K., Novak, I., Korosi, J., Reisch, J. 1976. Contribution to the Pharmacology of the Water Soluble Constituents From Ptelea trifoliata. Herba Hung, 15(3): 93.
O-METHYLPTELEFOLINIUM ipr rat Minker, E., Koltai, M., Blazso, G., Szendrei, K., Novak, I., Korosi, J., Reisch, J. 1976. Contribution to the Pharmacology of the Water Soluble Constituents From Ptelea trifoliata. Herba Hung, 15(3): 93.
PTELEFOLINE ipr rat Minker, E., Koltai, M., Blazso, G., Szendrei, K., Novak, I., Korosi, J., Reisch, J. 1976. Contribution to the Pharmacology of the Water Soluble Constituents From Ptelea trifoliata. Herba Hung, 15(3): 93.
RETICULINE 5-20 mg/kg ipr rat Dasgupta, S., Ray, A. B., Bhattacharya, S. K., Bose, R. 1979. Constituents of Pachygone ovata and Pharmacological Action of its Major Leaf Alkaloid. J Nat Prod, 42(4): 399-406.
RICIN 0.05 ug/kg ipr rbt *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Aesculus hippocastanum Horse Chestnut 1 0
Allium cepa Onion; Shallot 1 0
Allium sativum var. sativum Garlic 2 370
Aloe vera Bitter Aloes; Aloe 1 0
Angelica archangelica Garden Angelica; Angelica; Wild Parsnip 1 0
Angelica sinensis Dang Gui; Dong Quai; Dang Quai; Dang Qui; Dong Gui; Chinese Angelica 1 0
Annona cherimola Cherimoya 1 0
Annona glabra Pondapple 1 0
Annona montana Mountain Soursop 1 0
Annona muricata Soursop 1 0
Annona reticulata Custard Apple 1 0
Annona squamosa Sugar-Apple; Sweetsop 2 0
Apium graveolens Celery 1 0
Artemisia abrotanum Southernwood 1 0
Balanites aegyptiacus Desert Date; Soapberry Tree; dattier du desert (Fr.); dattier sauvage (Fr.); heglik (Fr.); Zachunbaum (Ger.); betu (India); hingotia (India); lalo (India); zachun (India); mirobalano de Egipto (Sp.) 1 0
Brassica oleracea var. gemmifera Brussels-Sprouts; Brussel-Sprout 1 142
Brassica oleracea var. sabellica l. Kale; Curly Kale; Kitchen Kale; Scotch Kale 1 520
Camellia sinensis Tea 1 422, 700
Capsicum annuum Bell Pepper; Green Pepper; Cherry Pepper; Sweet Pepper; Cone Pepper; Paprika 1 3, 831, 540
Capsicum frutescens Cayenne; Chili; Tabasco; Hot Pepper; Spur Pepper; Red Chili 1 107, 430