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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. Prostaglandin-Synthetase-Inhibitor

Prostaglandin-Synthetase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
2-(3-HYDROXY-4-METHOXY-STYRYL)-BENZOIC-ACID IC50=38 uM *
2-HYDROXY-3,4-DIMETHOXYBENZOIC-ACID-METHYL-ESTER IC50=23 uM *
ADOLAPIN-I cat; rat *
ADOLAPIN-II cat; rat *
ALLICIN *
ALOCTIN-A 10 ug/ml rat *
ANACARDIC-ACID *
ANZIAIC-ACID IC50=8.1 uM *
ARNEBIFURANONE 20 ug/ml (18.7% inhibition) *
ARNEBINOL IC50=29.5 uM *
ARNEBINOL ED50=29.5 uM *
ARNEBINONE 20 ug/ml (24.5% inhibition) *
BONINIC-ACID IC50=3.4 uM (ca ? aspirin, ca 4/3rds indomethcin) *
BROMELAIN hmn *
LUTEOLIN *
NESODINE *
PARTHENOLIDE *
TRANS-CIS-AJOENE IC50=5.1 uM *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Rosmarinus officinalis Rosemary 1 0
Salvia officinalis Sage 1 0
Santolina chamaecyparissus Lavender Cotton 1 0
Scutellaria galericulata Marsh Skullcap 1 0
Scutellaria lateriflora Mad-Dog Skullcap; Scullcap 1 0
Silybum marianum Milk Thistle; Lady's Thistle 1 0
Solanum tuberosum Potato 1 0
Stellaria media Chickweed; Common Chickweed 1 0
Tanacetum parthenium Feverfew 1 671, 324
Tanacetum vulgare Tansy 1 0
Taraxacum officinale Dandelion 1 0
Terminalia arjuna Arjun; Arjuna 1 1.7999999523162842
Teucrium polium Golden Germander 1 0
Theobroma cacao Cacao 1 0
Thymus vulgaris Common Thyme; Garden Thyme; Thyme 1 0
Tragopogon porrifolius Salsify 1 0
Tridax procumbens Coatbuttons; Mexican daisy 1 0
Trigonella foenum-graecum Fenugreek; Greek Clover; Greek Hay; Bockshornklee (Ger.); Alholva (Sp.) 1 0
Valeriana officinalis Valerian; Common Valerian; Garden-Heliotrope 1 0
Vitex agnus-castus Chaste-Tree 1 0