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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Prostaglandin-Synthetase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
2-(3-HYDROXY-4-METHOXY-STYRYL)-BENZOIC-ACID IC50=38 uM *
2-HYDROXY-3,4-DIMETHOXYBENZOIC-ACID-METHYL-ESTER IC50=23 uM *
ADOLAPIN-I cat; rat *
ADOLAPIN-II cat; rat *
ALLICIN *
ALOCTIN-A 10 ug/ml rat *
ANACARDIC-ACID *
ANZIAIC-ACID IC50=8.1 uM *
ARNEBIFURANONE 20 ug/ml (18.7% inhibition) *
ARNEBINOL ED50=29.5 uM *
ARNEBINOL IC50=29.5 uM *
ARNEBINONE 20 ug/ml (24.5% inhibition) *
BONINIC-ACID IC50=3.4 uM (ca ? aspirin, ca 4/3rds indomethcin) *
BROMELAIN hmn *
LUTEOLIN *
NESODINE *
PARTHENOLIDE *
TRANS-CIS-AJOENE IC50=5.1 uM *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Mentha arvensis var. piperascens Cornmint; Field Mint; Japanese Mint 1 0
Mentha spicata Spearmint; Hortela da Folha Miuda 1 0
Mentha x piperita Peppermint 1 0
Mentha x rotundifolia Applemint 1 0
Nelumbo nucifera Water Lotus 1 0
Ocimum basilicum Basil; Sweet Basil; Cuban Basil 1 0
Ocimum tenuiflorum Anise-Scented Basil 1 460
Olea europaea Olive 1 0
Ononis spinosa Spiny Restharrow; Restharrow; Hauhechel (Ger.) 1 0
Opuntia ficus-indica Indian Fig; Prickly Pear; Nopal; Nopalito 1 0
Origanum vulgare Common Turkish Oregano; Wild Oregano; Oregano; Pot Marjoram; Wild Marjoram; European Oregano 1 0
Passiflora incarnata Manzana de Mayo; Mayapple; Passionflower 1 0
Perilla frutescens Perilla 1 0
Phaseolus vulgaris Black Bean; Green Bean; Haricot Bean; Garden Bean; String Bean; Dwarf Bean; Field Bean; Flageolet Bean; French Bean; Kidney Bean; Navy Bean; Pop Bean; Popping Bean; Snap Bean; Wax Bean; Haricot Vert; Haricot 1 0
Physalis alkekingi Bladderherb; Lantern 1 0
Pimpinella anisum Anise; Sweet Cumin 1 2, 500
Plantago major Common Plantain 1 0
Plantago ovata Blond Psyllium; Ispaghula; Spogel Seeds; Psyllium; Indian Plantago 1 0
Prunella vulgaris Self-Heal; Heal-All 1 0
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 1 0