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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
POLYPHENOLS *
PROCYANIDIN-D2 IC29=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC11=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
QUERCETIN IC50=0.1-5 uM *
ROSMARINIC-ACID *
RUTIN IC75=2.5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
SCANDENOLIDE IC50=30-60uM *
SQUALENE Chemical Express, 7: 297, 1992.
TANNIN *
TAXIFOLIN Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
THEAFLAVIN IC50=3,604 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-DIGALLATE IC50=0.25 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THEAFLAVIN-MONOGALLATE-B IC50=0.62 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
THYMOQUINONE IC50 1 ug/ml Houghton, P.J., Zarka, R., Heras, B., and Hoult, J.R.S. 1994. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation. Planta Medica, 61: 33.
TOCOPHEROL Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
UMBELLIFERONE *
URSOLIC-ACID IC50=0.18 mM *
URUSHIOL Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
UVAOL *
VERBASCOSIDE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Sanguinaria canadensis Bloodroot 1 0
Sanguisorba minor Small Burnet 5 0
Sanguisorba officinalis Greater Burnet 4 340, 000
Santalum album White Sandalwood 1 0
Santolina chamaecyparissus Lavender Cotton 5 0
Sarcostemma acidum Soma 1 0
Sassafras albidum Sassafras 1 0
Satureja hortensis Summer Savory 3 113, 700
Satureja montana Winter Savory; Savory 5 88, 150
Saussurea lappa Costus; Kuth 1 0
Schinus molle California Peppertree; Mastic-Tree; Peruvian Peppertree 5 690, 000
Schinus terebinthifolius Brazilian Peppertree 4 0
Schisandra chinensis Chinese Magnolia Vine; Schizandra; Wu Wei Zu; Wu Wei Zi; Magnolia Vine; Five-Flavor-Fruit 1 0
Sclerocarya caffra Marula 1 300, 000
Scopolia carniolica Scopolia 5 0
Scrophularia scorodonia 2 0
Scutellaria baicalensis Chinese Skullcap; Huang Qin; Baikal Skullcap 1 222
Scutellaria churchilliana Hybrid Skullcap 1 0
Scutellaria galericulata Marsh Skullcap 2 35, 000
Scutellaria lateriflora Mad-Dog Skullcap; Scullcap 2 0