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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-1-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=10 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml *
PTEROSTILBENE IC50=20 uM *
PUNICIC-ACID *
RESVERATROL ED50=15 uM *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
ROSMARINIC-ACID IC58=1,000 uM *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Pinus strobus Eastern White Pine; White Pine 1 0
Pinus sylvestris Scotch Pine 2 0
Piper auritum Cordoncillo; Hierba Santa; Hoja Santa 2 579
Piper betel Betel Pepper 2 18, 025
Piper methysticum Kava-Kava 3 370
Piper nigrum Black Pepper; Pepper; White Pepper 5 1, 341.384000018239
Pistacia vera Pistachio 1 1.4600000381469727
Pisum sativum Pea 1 26.500000953674316
Plantago major Common Plantain 3 0
Plantago psyllium Psyllium 1 48
Platycodon grandiflorum Balloon Flower; Chieh-Keng; Jie-Geng 1 0
Plectranthus amboinicus Amboini Coleus; Country Borage; Cuban Oregano; French Thyme; Indian Borage; Soup Mint; Spanish Thyme; Mexican Mint 1 1, 400
Pogostemon cablin Patchouli 2 0
Polianthes tuberosa Tuberose 1 0
Polygonum aviculare Prostrate Knotweed 1 0
Polygonum multiflorum Chinese Cornbind; Fleeceflower; Fo Ti; He Shou Wu; Chinese Knotweed 2 37, 712.00000047684
Polymnia edulis Andean Jicama 1 10
Polypodium vulgare Common Polypody; Sweet Fern 1 0
Portulaca oleracea Purslane; Verdolaga 1 9, 300
Pourouma cecropiaefolia Tree Grape; Uvilla 1 0