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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-1-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=10 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
N-2'-METHYL-BUTYL-DECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-DODECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-HEXADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml (weak activity) Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-OCTADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
N-ISOBUTYL-TETRADECA-TRANS-2-TRANS-4-DIENAMIDE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PELLITORINE IC50 @ ug/ml Stohr, J. R., Xiao, P. G., Bauer, R. 1999. Isobutylamides and a New Methylbutylamide from Piper sarmentosum. Planta Med., 65(2): 175-177.
PINOSTROBIN IC36=100 ug/ml *
PTEROSTILBENE IC50=20 uM *
PUNICIC-ACID *
RESVERATROL ED50=15 uM *
RESVERATROL 50 uM/ Jang, M. S., Pezzuto, J. M. 1998. Resveratrol Blocks Eicosanoid Production and Chemically-Induced Cellular Transformation: Implication for Cancer Chemoprevention. Pharm Biol Suppl, 36: 28-34.
ROSMARINIC-ACID IC58=1,000 uM *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Nepeta cataria Catnip 3 4, 024
Nepeta racemosa Catmint 1 16
Nerium oleander Oleander 1 0
Nicotiana tabacum Tobacco 2 0
Ocimum basilicum Basil; Sweet Basil; Cuban Basil 5 3, 550, 266
Ocimum canum Hoary Basil 1 0
Ocimum gratissimum Agbo; Shrubby Basil 1 22, 110
Ocimum kilimandscharicum African Blue Basil; Kenyan Perennial Basil 1 6, 070
Ocimum sanctum Holy Basil; Tulsi 2 9, 990
Ocimum sp Basil 1 0
Ocimum suave Kenyan Tree Basil 1 2, 860
Ocimum tenuiflorum Anise-Scented Basil 6 6, 445
Oenanthe javanica Javan Water Dropwort 1 0
Olea europaea Olive 3 8.300000190734863
Ononis spinosa Spiny Restharrow; Restharrow; Hauhechel (Ger.) 1 0
Opuntia ficus-indica Indian Fig; Prickly Pear; Nopal; Nopalito 2 1.5600000619888306
Origanum majorana Marjoram; Sweet Marjoram 3 664, 904
Origanum minutiflorum Small-Flowered Oregano 1 125
Origanum onites Oregano; Pot Marjoram 1 0
Origanum vulgare Common Turkish Oregano; Wild Oregano; Oregano; Pot Marjoram; Wild Marjoram; European Oregano 5 1, 374, 300