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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
15-DESACETYLUNDULATONE IC50=0.047 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
16-EPIAFFININE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
17-METHOXY-28-NORISOIGUESTERIN IC50=0.028-0.37 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
18-HYDROXYISOSUNGUCINE IC50=0.1-0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
18-HYDROXYSUNGUCINE IC50=1-4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
2-(2,4-DIHYDROXYPHENYL)-5,6-METHYLENEDIOXYBENZOFURAN EC50=27 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
20-EPIANTIRHINE IC50=7.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
28-NOR-IGOIGUESTERIN-17-CARBALDEHYDE IC50=0.080-0.094 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3,4,5-TRIMETHOXYPHENYL(6'-O-GALLOYL)-O->D-GLUCOPYRANOSIDE IC50=3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-HYDROXY-6'-DESMETHYL-9-O-METHYL-THALIFABORAMINE IC50=0.05-0.24 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-HYDROXY-THALIFABORAMINE IC50=0.01-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-METHOXYSAMPANGINE IC50=0.09-0.28 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-METHYLNAPHTHARAZIN IC50=5.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-O-BENZOYLHOSLOPPONE IC50=0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
5,7-DIMETHOXY-8-(3'-HYDROXY-3'-METHYL-1'-BUTENE) IC50=8.8-16.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6'-DESMETHYL-THALIFABORAMINE IC50=0.01-0.15 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ACETYLSWIETENOLIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ALPHA-TIGLOYLOXYGLAUCARUBOL IC50=0.257 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-DEACETYLKHIVORIN IC50=5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-EPIDIONCHOPHYLLINE-A IC50=0.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Artocarpus altilis Breadfruit 1 0
Artocarpus heterophyllus Jackfruit 2 0
Artocarpus integrifolia 1 3, 000
Asimina triloba Pawpaw 1 0
Aspalathus linearis Rooibos; Kaffree Tea; Red Bush Tea 1 26.399999856948853
Asparagus officinalis Asparagus 1 0
Aspidixia angulata 1 0
Astragalus membranaceus Huang-Chi; Huang Qi 1 0
Atractylodes lancea Cang Zhu 1 0
Avena sativa Oats 1 310
Avicennia alba 1 160
Avicennia marina 1 6, 000
Avicennia officinalis 1 1, 950
Avicennia tomentosa 1 100
Azadirachta indica Neem 6 1, 010
Balanops australiana 1 180
Barosma betulina Buchu 1 0
Basella alba Vinespinach 1 0
Bauhinia vahlii 1 0
Berberis vulgaris Barberry 6 266, 900