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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
CHRYSOSPLENETIN IC50=23 uM *
CHRYSOSPLENOL-D IC50=32 uM *
CINCHONIDINE 150-500 mg/man/4 x day *
CINCHONINE LD50=152 (ipr rat) Merck 11th Edition
CIRSILINEOL IC50=36 uM *
CLAUSARIN IC50=0.1-0.7 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
COCSULINE IC50=15.56 ug/mL *
COLCHICINE 500 ug/10x/day/man Martindale's 28th
COLUMBAMINE 0.72 ug/ml *
CONOPHARYNGINE IC50=0.24-0.29 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORONARIDINE IC50=1.3-2.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORYNANTHEDINE IC50=41 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORYNANTHEINE IC50=81 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CORYNANTHINE IC50=>200 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
COSTARICINE IC50=0.1-0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
COWAXANTHONE IC50=1.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CROSTPARINE IC50=2.1-3.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CRYPTOHEPINE IC50=0.8-1.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CRYPTOLEPINE IC50=0.031 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
CRYPTOLEPINE IC50=0.1-0.2 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Ocimum canum Hoary Basil 3 0
Ocimum gratissimum Agbo; Shrubby Basil 2 1, 140
Ocimum suave Kenyan Tree Basil 1 0
Ocimum tenuiflorum Anise-Scented Basil 3 7, 090
Oenanthe aquatica Water Fennel; Water Hemlock 1 0
Oenanthe crocata Water Dropwort 1 0
Oenothera biennis Evening-Primrose 3 207, 000
Olea europaea Olive 5 0
Ononis spinosa Spiny Restharrow; Restharrow; Hauhechel (Ger.) 1 0
Opopanax chironium Hercules All Heal; Opopanax 1 0
Opuntia ficus-indica Indian Fig; Prickly Pear; Nopal; Nopalito 1 0
Origanum compactum 1 70
Origanum majorana Marjoram; Sweet Marjoram 4 13, 600
Origanum onites Oregano; Pot Marjoram 1 40
Origanum vulgare Common Turkish Oregano; Wild Oregano; Oregano; Pot Marjoram; Wild Marjoram; European Oregano 4 18, 600
Paeonia japonica 1 5, 000
Paeonia lactiflora Chih-Shao; Peony; Common Garden Peony; White Peony; Bai Shao (Chinese) 1 0
Paeonia moutan Moutan; Tree Peony 1 0
Paeonia suffruticosa Moutan; Tree Peony; Moutan Peony 1 0
Palaquium grande 1 7