Chemical CRYPTOLEPINE

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Activity Sort descending	Dosage	Reference
Antiaggregant	not available	Bezanger-Beauquesne*, L. Noveautes En Phytotherapie. Sixieme Revue. Plantes medicinales et phytotherapie, 23: 46-76, 1989.
Antibacterial	MIC=<8-250 ug/ml	Duke, 1992 *
Antiedemic	not available	Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antihistaminic	not available	Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antimalarial	IC50=0.031 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antimalarial	IC50=0.1-0.2 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial	IC50=0.031 ug/ml	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial	IC50=0.1-0.2 uM	Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiseptic	not available	Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
Candidicide	MIC=31 ug/ml	Duke, 1992 *
Cytotoxic	1 ug/mL	Duke, 1992 *
Fungistat	not available	Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive	not available	Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
Hypothermic	not available	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
Topoisomerase-I-Inhibitor	5 uM	Bonjean, K., et al. 1998. The DNA Intercalating Alkaloid Cryptolepine Interferes with Topoisomerase II and Inhibits Primarily DNA Synthesis in B16 Melanoma Cell. Biochemistry, 37: 5136-5146.
Topoisomerase-II-Inhibitor	0.5-50 uM	Duke, 1992 *
Vasodilator	not available	Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.