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Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Sort descending Dosage Reference
ARTEMISININ ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) Duke, 1992 *
ARTESUNATE not available Duke, 1992 *
ASCARIDOLE 0.05-0.1 uM Duke, 1992 *
ASIMICIN IC50=4 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE 50 mg/kg/day ipr mus Duke, 1992 *
ATAPHILLININE 50 mg/kg (ipr mus) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE IC50=0.14-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE IC50=3 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE IC50=12 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE not available Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE IC50=0.84 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE 50 uM Duke, 1992 *
BERBERASTINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 50 uM Duke, 1992 *
BETA-DICHROINE not available Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE 5.6 ug/ml Duke, 1992 *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Sort descending Common Name Chemical Count Total Parts Per Million
Myristica fragrans Mace; Nutmeg; Muskatnussbaum (Ger.); nogal moscado (Sp.); nuez moscada (Sp.) 2 0
Myroxylon balsamum Peru Balsam; Tolu Balsam 1 0
Myrrhis odorata Garden Myrrh; Myrrh; Sweet Chervil; Sweet Cicely; Cicely 1 47, 500
Myrtus communis Myrtle; Myrte (Ger.); Arrayan (Sp.); Mirto (Sp.) 5 1, 048
Nandina domestica Heavenly Bamboo; Sacred Bamboo; Southern Heaven Bamboo; Nanten (Jap.) 2 0
Narcissus tazetta Daffodil 1 0
Nasturtium officinale Berro; Watercress 1 0
Nelumbo nucifera Water Lotus 2 0
Nepeta cataria Catnip 1 10, 300
Nepeta racemosa Catmint 3 164
Nerium oleander Oleander 5 43, 000
Neurolaena lobata Bitter Wood; Contragavilana 2 0
Newcastelia viscida not available 1 0
Nicotiana glauca Tree Tobacco 1 21, 000
Nicotiana tabacum Tobacco 2 10, 000
Nigella sativa Black Cumin; Roman Coriander; Fennel-Flower; Nutmeg-Flower; Black Caraway 1 1, 000
Nuytsia floribunda not available 1 17, 000
Nymphoides peltatum not available 1 0
Ocimum americanum not available 1 0
Ocimum basilicum Basil; Sweet Basil; Cuban Basil 7 16, 944