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Biological Activity Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Sort descending Dosage Reference
ARTEMISININ IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) Duke, 1992 *
ARTEMISININ ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTESUNATE not available Duke, 1992 *
ASCARIDOLE 0.05-0.1 uM Duke, 1992 *
ASIMICIN IC50=4 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE 50 mg/kg/day ipr mus Duke, 1992 *
ATAPHILLININE 50 mg/kg (ipr mus) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE IC50=0.14-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE IC50=3 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE IC50=12 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE not available Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE IC50=0.84 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE 50 uM Duke, 1992 *
BERBERASTINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 0.14-0.36 ug/ml Duke, 1992 *
BERBERINE 50 uM Duke, 1992 *
BETA-DICHROINE not available Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE 5.6 ug/ml Duke, 1992 *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Sort descending Common Name Chemical Count Total Parts Per Million
Mentha x rotundifolia Applemint 2 0
Menyanthes trifoliata Bogbean; Buckbean; Bog Myrtle; Marsh Clover; Marsh Trefoil; Water Trefoil 4 54, 000
Mercurialis annua Annual Mercury 1 0
Mesua ferrea not available 1 2, 120
Mesua myrtifolia not available 1 100
Metrosideros excelsa not available 1 1, 000
Metrosideros sclerocarpa not available 3 1, 348
Micromeria varia Madeiran 'Hyssop' 3 12
Mimusops littoralis not available 1 0
Mitrephora heyneana not available 1 0
Monarda didyma Beebalm; Oswego Tea 1 0
Morinda citrifolia Indian Mulberry; Noni 4 1, 000
Moringa oleifera Ben Nut; Drumstick Tree; Horseradish Tree; Benzolive Tree; Moringa; West Indian Ben; Jacinto (Sp.) 1 0
Morus alba Sang-Pai-Pi; White Mulberry 4 123, 900
Morus serrata not available 1 0
Murraya koenigii Curry Leaf Tree; Curry Leaf; Indian Curry Tree 2 75.30000000447035
Murraya sp None 1 0
Musa x paradisiaca Banana; Plantain 2 0
Myrciaria dubia Camu-camu (Eng.,Peru,Scn.,Sp.); Rumberry (Eng.); Camo Camo (Peru); Araza de Agua (Sp.); Camu-camu Negro (Peru); Guapuro Blanco (Bol.) 2 0
Myrica cerifera Bayberry; Wax Myrtle; Southern Bayberry; Candle-Berry 1 0