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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ARTEMISININ IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) *
ARTEMISININ ED50=90 mg/kg orl mus Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTEMISININ ED95=1,000 mg/man/day Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ARTESUNATE *
ASCARIDOLE 0.05-0.1 uM *
ASIMICIN IC50=4 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ATALAPHILLININE 50 mg/kg/day ipr mus *
ATAPHILLININE 50 mg/kg (ipr mus) Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
AUGUSTINE IC50=0.14-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
AZADIRADIONE IC50=3 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AZADIRONE IC50=12 ug/ml Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
BEBEERINE Merck 11th Edition
BENZOISOQUINOLONE-5-10-DIONE IC50=0.84 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BERBERASTINE 50 uM *
BERBERASTINE 0.14-0.36 ug/ml *
BERBERINE 0.14-0.36 ug/ml *
BERBERINE 50 uM *
BETA-DICHROINE Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
BETA-SELINENE IC50=>50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
BETA-SELININE-HYDROPEROXIDE 5.6 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Panax ginseng Chinese Ginseng; Oriental Ginseng; Ginseng; Korean Ginseng 6 498, 800
Panax japonicus Japanese Ginseng 1 0
Panax notoginseng Sanchi Ginseng 1 0
Panax quinquefolius American Ginseng; Ginseng 4 2, 000
Pancratium maritimum Sea Daffodil 1 0
Papaver somniferum Opium Poppy; Poppyseed Poppy 1 0
Passiflora incarnata Manzana de Mayo; Mayapple; Passionflower 4 210
Pastinaca sativa Parsnip 2 0
Pausinystalia johimbe Yohimbe 4 0
Pedicularis longiflora 1 0
Peganum harmala Harmel; Syrian Rue 2 0
Pelargonium citrosum Citrosa 1 2
Pelargonium graveolens Rose Geranium; Scented Geranium 1 0
Peperomia pelucida Pepper elder; Yerba de la plata 1 0
Perilla frutescens Perilla 1 0
Persea americana Avocado 1 0
Petasites hybridus European Butterbur 1 0
Petroselinum crispum Parsley 6 171, 386.67999994755
Peucedanum ostruthium Masterwort 2 15, 000
Peumus boldus Boldo 4 12, 470