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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
OPHIOBOLIN-A IC50=0.5-0.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OSTHOL IC50=25.1 ug/ml Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
OSTHOLE *
OSTRUTHIN *
OXYACANTHINE IC50=0.3 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PALMATINE *
PATCHOULENE IC50=108 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHAEANTHINE IC50=1.43 ug/ml (1/10 x chloroquine) *
PHEANTHINE IC50=1,400 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PHLORIDZIN *
PHLORIZIN *
PIQUEROL-A IC50=100 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLEIOCARPAMINE IC50=6-20 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.178-0.189 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PLUMBAGIN IC50=0.3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PRIEURIANIN IC50=14.08 ug/mL) *
PRISTIMERIN IC50=0.19-28 ug/ml *
PSYCHOTRINE IC50=0.1-0.4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
PUNICALAGIN 2-8 ug/ml *
PYCNAMINE IC50=0.15 ug/mL (ca 1 x chloroquine) *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Teucrium polium Iberian Golden Germander; Golden Germander 4 68
Teucrium scordium Water Germander 3 0
Teucrium scorodonia Germander; Wood Germander 2 6, 000
Theobroma cacao Cacao 2 0
Thespesia populnea Indian tulip tree 2 78, 800
Thevetia peruviana Peruvian Yellow Oleander; Luckynut; Yellow Oleander; Oleandre Jaune (Fr.); Thevetie (Ger.); Loandro-Amarelo (Port.); Adelfa Amarilla (Sp.); Cabalonga (Sp.); Chirca (Sp.) 3 13, 500
Thymus broussonettii Moroccan Thyme 1 0
Thymus capitatus 'Sicilian' Thyme; Spanish Origanum; Spanish Thyme 1 0
Thymus cilicicus 'Anatolian' Thyme 3 141
Thymus funkii Funk's Thyme 3 53
Thymus longicaulis Kekik; Tas Kekik 1 0
Thymus mastichina Spanish Marjoram 1 75
Thymus saturejoides Moroccan Savory Thyme 1 10
Thymus serpyllum Creeping Thyme 2 13, 900
Thymus vulgaris Common Thyme; Garden Thyme; Thyme 3 75, 300
Thymus zygis Spanish Thyme 1 0
Tilia sp. Basswood; Lime; Linden 1 0
Tovomita brasiliensis 1 0
Tovomita excelsa 1 83.9000015258789
Tovomita mangle 1 0