Sophora subprostrata | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

Back to previous

Download a full report in PDF format

Common name(s)

Shan Dou Gen

How used

Medicinal

Data Views

Activities: 245

Chemicals w/Activities: 18

All Chemicals: 28

CSV Excel PDF

Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
Click on column headings to sort table by that column
# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
0	4',7-DIHYDROXY-6,8-BIS(3-METHYL-2-BUTENYL)-FLAVANONE	Root	--	--	--	*
11	ANAGYRINE	Root	--	--	--	*
Antiarrhythmic * Antiedemic * AntiRSV * Antiviral * Cardiotonic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cathartic * Diuretic * Nematistat Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Oxytoxic * Tachycardic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Teratogenic 30 mg/kg *
2	ARSENIC	Root	--	0.2	-0.20	*
Anorexic Forest H. Nielsen, USDA, Grand Forks, various publications. Pesticide *
28	CALCIUM	Root	--	18600.0	1.23	*
Antiallergic 500 mg/day * Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiarrhythmic 500-1,500 mg * Antiarthritic 1,000 mg/day * Antiatherosclerotic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Anticlimacteric 1,000-1,500 mg/day * Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenopausal 1,000-1,500 mg/day * Antiobesity * Antiosteoporotic 500-2,000 mg/day * Antiperiodontitic 750 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. AntiPMS 1 g/day * Antirheumatic 1,000 mg/day * Antistress 500-1,500 mg/day * Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anxiolytic 500-1,500 mg/day * Calcium-Channel-Blocker * Diuretic * Hypocholesterolemic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 1 g/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Laxative 1,000-1,200 mg * Tranquilizer 500-1,500 mg/day * Vasodilator *
12	COPPER	Root	--	5.0	-0.74	*
Antianemic * Antiarthritic * Antidiabetic 2-4 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antifatigue * Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Cardioprotective * Contraceptive Martindale's 28th Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Immunomodulator * Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
0	D-MATRINE-N-OXIDE	Root	--	--	--	*
32	DAIDZEIN	Root	--	--	--	*
Antialcoholic * Antiarrhythmic * Anticancer * Anticephalagic * Antidipsomanic 150 mg/kg/day * Antiestrogenic * Antihemolytic * Antiinflammatory * Antileukemic IC50=>10 ug/ml Life Sciences 55: 1061. Antimelanomic * Antimicrobial * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antiosteoporotic * Antioxidant 1/4 quercetin * Antiproliferative * Antiradicular 1/4 quercetin * Antispasmodic * Antitumor-Promoter * Antiviral * Aromatase-Inhibitor IC28=1 uM/l Journal of Medicinal Food 2: 235.1999. Cancer-Preventive * Coronary-Dilator * Estrogen-Agonist 0.1-1 uM/l Journal of Medicinal Food 2: 139.1999. Estrogenic EC50=0.1-25 uM/l * Fungicide >100 * Hypotensive ivn Foster, S. and Yue, C-G. 1992. Herbal Emissaries-Bringing Chinese Herbs to the West. Healing Arts Press, Rochester VT. 356 pp. Lipase-Inhibitor * Quinone-Reductase-Inducer Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630. Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237. Topoisomerase-II-Inhibitor IC50=3.9 mM Sun, N. J., Woo, S. H., Cassady, J. M., Snapka, R. M. 1998. DNA Polymerase and Topoisomerase II Inhibitors From Psoralea corylifolia. J Natural Products, 61: 362-366. Uterotrophic EC50=0.1-25 uM/l Journal of Medicinal Food 2: 227.1999. VEGF-Inhibitor *
81	GENISTEIN	Root	--	--	--	*
Abortifacient Cooper-Driver, G. A., Chemical substances in plants toxic to animals, pp. 213-47 in Rechcigl, M., Jr., ed. CRC Handbook of Naturally Occurring Food Toxicants, CRC Press, Boca Raton, 1983, 339 pp. Aldose-Reductase-Inhibitor IC50=10 uM * Alpha-Reductase-Inhibitor IC50=35 uM * Antiaggregant 1-10 ug/ml Medline (post 1990 searches filed in my computer) Antiangiogenic 150 uM * Antiatherosclerotic Journal of Medicinal Food 2: 163.1999. Anticancer (Breast) IC50=2.6-6.7 ug/ml * Anticarcinomic (Breast) IC50=?640 uM Medline (post 1990 searches filed in my computer) Anticlimacteric Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705. Antiendoccytotic 100 ug/ml Medline (post 1990 searches filed in my computer) Antiestrogenic * Antifertility * Antihemolytic * Antiimplantation * Antiinflammatory Journal of Medicinal Food 2: 179.1999. Antiischemic Medline (post 1990 searches filed in my computer) Antileukemic >50 ug/ml (185 uM) * Antileukemic IC50=0.010 ug/ml Life Sciences 55: 1061. Antileukotriene IC50=10-15 uM Medline (post 1990 searches filed in my computer) Antilymphomic * Antimelanomic Medline (post 1990 searches filed in my computer) Antimicrobial * Antimitogenic IC50=12 uM * Antimutagenic ID50=50-100 nM Maga, J.A. Contribution of Phenolic Compounds to Smoke Flavor. Phenolic Compounds in Food and Their Effects on Health, Ch.13. Antineuroblastomic * Antiosteoporotic * Antioxidant Phenolic Compounds in Food and Their Effects on Health, 64. Antiproliferative 5-45 uM * Antiprostatadenomic 8-27 ug/ml Medline (post 1990 searches filed in my computer) Antiprostatitic IC50=35 uM * Antispasmodic IC50=34 uM * Antitumor (Breast) * Antitumor (GI) * Antitumor (Ovary) * Antitumor (Prostate) * Antitumor (Stomach) * Antiulcer? * Antiviral * Apoptotic * Aromatase-Inhibitor IC30=1 uM/l Journal of Medicinal Food 2: 235.1999. Calcium-Antagonist 50 uM gpg * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective Journal of Medicinal Food 2: 163.1999. Catechol-O-Methyltransferase-Inhibitor * Cytotoxic >50 ug/ml (185 uM) Medline (post 1990 searches filed in my computer) Cytotoxic IC89=10 ug/ml Planta Medica, 57: A113, 1991. DOPA-Decarboxylase-Inhibitor * Estrogen-Agonist 0.1-1 uM/l Journal of Medicinal Food 2: 139.1999. Estrogenic EC50=0.1-25 uM/l * Flatulent * Fungicide 2.5 mM Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995. Fungicide ED50=50->100 * Fungistat IC34=200 uM * Histidine-Kinase-Inhibitor IC50=110 uM Medline (post 1990 searches filed in my computer) Hypocholesterolemic ED50=0.5 mg/kg * Immunostimulant 2-20 mg/kg orl mus * Lipase-Inhibitor * MAO-Inhibitor IC50=60-140 uM * MAO-Inhibitor IC50=95 * MDR-Inhibitor 200 uM Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93. NADH-Ubiquinone-Oxidoreductase-Inhibitor * Natriuretic * Ornithine-Decarboxylase-Inhibitor * Peroxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Phytoalexin Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Pituitary-sensitizer Medline (post 1990 searches filed in my computer) PTK-Inhibitor 10-100 uM * Quinone-Reductase-Inducer IC50=4.6 ug/ml * Topoisomerase-I-Inhibitor IC50=250 ppm * Topoisomerase-I-Inhibitor 1-10 ug/ml Okura, A., Arakawa, H., Oka, H., Yoshinari, T., Monden, Y. 1988. Effect of Genistein on Topoisomerase Activity and on the Growth of [VAL 12]HA-RAS-Transformed NIH 3T3 Cells. Biochem Biophys Res Commun, 157: 183-189. Topoisomerase-II-Inhibitor 2-7.5 ug/ml * Topoisomerase-II-Inhibitor IC50=30 ug/ml Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225. Topoisomerase-II-Inhibitor 20 uM Markovits, J., et al. 1989. Inhibitory Effects of the Tyrosine Kinase Inhibitor Genistein on Mammalian DNA Topoisomerase II. Cancer Research, 49: 5111-5117. Topoisomerase-II-Inhibitor IC50=1-150 uM * Topoisomerase-II-Poison Journal of Medicinal Food 2: 167.1999. Trypanosomastat Medline (post 1990 searches filed in my computer) Tyrosine-Kinase-Inhibitor * Uterotrophic ED50=0.5 mg/kg * Uterotrophic EC50=0.1-25 uM/l * VEGF-Inhibitor *
6	IRON	Root	--	130.0	-0.25	*
Antiakathisic Martindale's 29th Antianemic Martindale's 29th Anticanker * Anticheilitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antimenorrhagic 100 mg/day/wmn/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Prooxidant *
1	L-MAACKIAIN	Root	--	--	--	*
Quinone-Reductase-Inducer IC50=>13.4 uM *
0	L-PTEROCARPIN	Root	--	--	--	*
21	LUPEOL	Root	--	--	--	*
Antiangiogenic 30-50 ug/ml * AntiEBV * Antiedemic * Antiflu * Antihyperglycemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory 1/3 indomethacin * Antilithic 25 mg/kg/day * Antimalarial IC50=46.8 ug/ml Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986. Antioxalate 25 mg/kg/day * Antioxidant 25 mg/kg/day * Antiperoxidant 25 mg/kg/day * Antiprostaglandin * Antirheumatic * Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiurethrotic * Antiviral * Cytotoxic 50-500 ppm * FPTase-Inhibitor IC50=65 ug/ml * Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * TOPO-2-Inhibitor IC50=10.4 uM *
65	MAGNESIUM	Root	--	1880.0	-0.36	*
Antiaggregant 400 mg/day * Antialcoholic * Antianginal 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antianorectic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antianxiety 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiarrhythmic 400 mg/day * Antiarthritic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiatherosclerotic 400 mg/day * Anticephalagic * AntiCFS * Anticlimacteric 500-750 mg/day * Anticonvulsant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp. Anticoronary 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidiabetic 400-800 mg/man/day * Antidysmenorrheic 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiendometriotic 500 mg/day * Antienterotic * Antiepileptic 450 mg/day * Antifatigue * Antifibromyalgic 200-300 mg 3x/day * Antigastrotic * Antiglaucomic * Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antihypoglycemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiinflammatory 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). AntiLyme 400-1,000 mg * Antimastalgic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antimenopausal 500-750 mg/day * Antimigraine 200 mg/day/man Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antimitral-valve-prolapse * AntiMS * Antinephrolytic * Antineurotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antiosteoporotic 500-1,000 mg/day/wmn/orl * Antiplaque 500-1,000 mg/day * AntiPMS 400-800 mg/day/wmn orl * AntiPMS 400-800 mg/day/wmn/orl * AntiRaynaud's 280-350 mg/day * Antiretinopathic 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antispasmodic * Antispasmophilic 500 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antistress 500-750 mg/day * Antistroke 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Antisyndrome-X 400 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Anxiolytic 500-750 mg/day * Calcium-Antagonist * Cardioprotective * CNS-Depressant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp. Diuretic * Hypocholesterolemic 400 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Hypotensive 260-500 mg/day * Immunomodulator * Insulinogenic 400 mg/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Laxative 300-500 mg/day * Litholytic * Myorelaxant 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Neurotransmitter * Tranquilizer 500-750 mg/day * Uterorelaxant 100 mg 4 x/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Vasodilator *
14	MANGANESE	Root	--	14.0	-0.38	*
Antialcoholic Forest H. Nielsen, USDA, Grand Forks, various publications. Antianemic Martindale's 28th Antiarthritic * Antidiabetic 3-5 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antidiabetic 10-30 mg/man/day * Antidiscotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidyskinetic Martindale's 28th Antiepileptic 450 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antiosteoporotic * Antiototic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antioxidant * AntiPMS * Antisyndrome-X 10-30 mg/man/day Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95 Hypoglycemic 10-30 mg/man/day *
21	MATRINE	Root	--	--	--	*
Antiallergic * Antianaphylactic * Antiarrhythmic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 407. Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antidermatitic * Antiedemic 15-25 mg/kg ims mus * Antihistaminic * Antiinflammatory 15-25 mg/kg ims mus * Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiulcerogenic * Cardiorelaxant * CNS-Inhibitor * Convulsant * Hypotensive * Hypothermic * Immunostimulant * Immunosuppressant * Inotropic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Paralytic * Pesticide * Protisticide *
1	MERCURY	Root	--	0.1	-0.12	*
Nephrotoxic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
0	METHYL-CYTISINE	Root	--	--	--	*
5	OXYMATRINE	Root	--	--	--	*
Antiarrhythmic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 407. Antiasthmatic * Antitumor * Antiulcerogenic * Immunostimulant 2-10 ug/ml *
14	POTASSIUM	Root	--	820.0	-1.10	*
Angiotensin-Receptor-Blocker * Antiarrhythmic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antifatigue Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antihypertensive * Antispasmodic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Antistroke * Anxiolytic * Beta-Blocker * Cardioprotective 3,000-5,000 mg * Cardiotoxic 18,000 mg/man/day * Diuretic * Hypotensive * Vasodilator *
1	SODIUM	Root	--	76.0	-0.48	*
Hypertensive Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.

Show all rows.

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Sophora subprostrata (Fabaceae)

Data Views