Rheum rhabarbarum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Rhubarb

How used

Medicinal

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Activities: 550

Chemicals w/Activities: 81

All Chemicals: 144

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
30	(+)-CATECHIN	Root	--	--	--	*
ACE-Inhibitor IC50=0.155 mM/l * ACE-Inhibitor 0.24 mg/ml rbt (weak activity) * Antiaggregant IC68=200 ug/ml * Anticoagulant * Anticomplementary 1/2 aspirin * AntiHIV EC50=4 ug/ml * Antiinflammatory IC50=40-943 uM (cf indomethacin IC50=1 uM) * Antimutagenic ID50=50-100 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Antioxidant * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiprostaglandin IC50=40-943 uM (cf indomethacin IC50=1 uM) * Antiradicular Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiulcer * Beta-Adrenergic Receptor Blocker 10 uM (weak activity) Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447. cAMP-Phosphodiesterase-Inhibitor * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic * COX-1-Inhibitor IC50=183-279 uM (cf indomethacin IC50=1 uM) * COX-2-Inhibitor IC50=546-5,910 uM (cf indomethacin IC50=1 uM) * Cyclooxygenase-Inhibitor * Cytotoxic TC50=>100 ug/ml * Dermatitigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hemostat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hepatoprotective Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Immunostimulant Economic & Medicinal Plant Research, 1: 124. Neuroprotective 1-10 uM * NO-Inhibitor IC11=250 uM * Phagocytotic Economic & Medicinal Plant Research, 1: 124. Vasoconstrictor Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980. Xanthine-Oxidase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
0	(+)-CATECHIN-5-O-GLUCOSIDE	Root	--	--	--	*
38	(-)-EPICATECHIN	Root	--	--	--	*
5-Lipoxygenase-Inhibitor IC50=22-50 uM/l * ACE-Inhibitor IC50=0.216 mM/l * ACE-Inhibitor 0.5 mg/ml rbt (weak activity) * Allelochemic Hanke, F. J., Natural Products as a Resource for Biologically Active Compounds, Thesis, U. Cal (Santa Cruz), 1986, 252 pp Antiaggregant * Antianaphylactic * Antibacterial * Antidiabetic 30 mg/kg rat * AntiEBV Economic & Medicinal Plant Research, 6: 189. Antihepatitic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. AntiHIV EC50=2 ug/ml * Antihyperglycemic * Antiinflammatory * Antileukemic Economic & Medicinal Plant Research, 6: 189. Antileukotriene * Antilipoperoxidant * Antimutagenic * Antioxidant IC50=6.3 ug/ml * Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiviral EC50=2 ug/ml * Beta-Adrenergic Receptor Blocker 10 uM Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardiotonic * Choline-Sparing * COMP-Inhibitor Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045. Cytotoxic TC50=>100 ug/ml * Hypocholesterolemic * Hypoglycemic * Immunostimulant * Insulinogenic Economic & Medicinal Plant Research, 6: 170. Lipoxygenase-1-Inhibitor IC50=60 mM * Lipoxygenase-Inhibitor IC50=140 uM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Lipoxygenase-Inhibitor IC97=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Pancreatogenic * Pesticide * Reverse-Transcriptase-Inhibitor 10 ng/ml McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Vasodilator uM McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Xanthine-Oxidase-Inhibitor IC50=>40 Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
7	(-)-EPICATECHIN-3-O-GALLATE	Root	--	--	--	*
ACE-Inhibitor ED50=0.08 mM/ * AntiHIV EC50=1 ug/ml * Antioxidant IC50=0.16 ug/ml * Antiviral EC50=1 ug/ml * Cytotoxic TC50=>100 ug/ml * Methyl-Guanidine-Inhibitor 2.5 mg/kg/day McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82. Nephroprotective 2.5 mg/kg/day McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
0	1,2,6-TRI-O-GALLOYL-GLUCOSE	Root	--	--	--	*
0	1,6-DI-O-GALLOYL-GLUCOSE	Root	--	--	--	*
0	1-O-GALLOYL-GLYCEROL	Root	--	--	--	*
0	2-O-CINNAMOYLGLUCOGALLIN	Root	--	--	--	*
0	3,3',5-TRIHYDROXY-4'-METHOXYSTILBEN-3-BETA-D-GLUCOPYRANOSIDE	Plant	--	--	--	*
0	3,5,4'-TRIHYDROXYSTILBENE-4'-O-(6'-O-GALLOYL)-GLUCOSIDE	Root	--	--	--	*
0	3,5,4'-TRIHYDROXYSTILBENE-4'-O-GLUCOSIDE	Root	--	--	--	*
0	4-(P-HYDROXYPHENYL)BUTANONE-O-GLUCOSIDE	Root	--	--	--	*
0	6-HYDROXYMUSIZIN-8-O-GLUCOSIDE	Root	--	--	--	*
0	6-O-GALLOYL-GLUCOSE	Root	--	--	--	*
16	ACETIC-ACID	Pt	--	--	--	*
Acidulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antibacterial 5,000 ppm * Antiotitic Martindale's 28th Antisalmonella * Antivaginitic 1-2% * Expectorant Martindale's 28th Fungicide Martindale's 29th Keratitigenic * Mucolytic Martindale's 29th Osteolytic * Perfumery FEMA 6,000-40,000 ppm Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Protisticide Martindale's 29th Spermicide Martindale's 28th Ulcerogenic HerbalGram No. 20, page 9. Verrucolytic *
0	ALOE-EMODIN-8-O-GLUCOSIDE	Root	--	--	--	*
32	ALPHA-TOCOPHEROL	Pt	2.0	48.0	-1.00	*
Antialzheimeran * Antianginal * Antiarthritic * Antiasthmatic * Antiatherosclerotic Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Anticancer * Anticataract * Anticonvulsant Synergen * Antidementia * Antidiabetic Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Antiinfarctal Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Antiinfertility * Antiischemic * Antimaculitic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuropathic * Antioxidant 5 x quercetin * Antioxidant IC34=10 uM * Antiparkinsonian * Antiradicular 5 x quercetin * Antiretinotic * Antirheumatic * Antistroke * Antitumor * Antitumor (Bladder) * Antitumor (Prostate) * Antitumor (Stomach) * Antitumor-Promoter * Cancer-Preventive * Cardioprotective * Circulotonic * Immunomodulator *
32	ALPHA-TOCOPHEROL	Leaf	1197.0	1238.0	3.07	*
Antialzheimeran * Antianginal * Antiarthritic * Antiasthmatic * Antiatherosclerotic Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Anticancer * Anticataract * Anticonvulsant Synergen * Antidementia * Antidiabetic Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Antiinfarctal Soumyanath, A. Ed. 2006. Traditional Medicines for Modern Times - Antidiabetic Plants. CRC Press, Taylor & Francis Group. Boca Raton, FL. 314 pp. Antiinfertility * Antiischemic * Antimaculitic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antineuropathic * Antioxidant 5 x quercetin * Antioxidant IC34=10 uM * Antiparkinsonian * Antiradicular 5 x quercetin * Antiretinotic * Antirheumatic * Antistroke * Antitumor * Antitumor (Bladder) * Antitumor (Prostate) * Antitumor (Stomach) * Antitumor-Promoter * Cancer-Preventive * Cardioprotective * Circulotonic * Immunomodulator *
5	ALUMINUM	Pt	1.0	80.0	--	*
Antisilicotic Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. Antivaginitic Martindale's 28th Candidicide Martindale's 28th Encephalopathic Martindale's 29th Pesticide *
0	ANHYDRORHAPONTIGENIN	Root	--	--	--	*

List of all activity chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Rheum rhabarbarum (Polygonaceae)

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