Hemidesmus indicus | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Indian Sarsaparilla

How used

Medicinal

Data Views

Activities: 149

Chemicals w/Activities: 9

All Chemicals: 19

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Exclude ubiquitous chemicals - View the list of ubiquitous chemicals

List of all chemical
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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
10	ALPHA-AMYRIN	Root	--	--	--	*
Analgesic * Antiedemic IC43=40 mg/kg ipr rat * Antiinflammatory IC71=1,000 ppm orl * Antinociceptive * Antitumor * Antiulcer * Cytotoxic 50-400 * Gastroprotective * Hepatoprotective * Insectifuge *
9	BETA-AMYRIN	Root	--	--	--	*
Analgesic * Antiedemic IC27=40 mg/kg ipr rat * Antiinflammatory * Antinociceptive * Antiulcer * Gastroprotective * Hepatoprotective * Larvicide * Mosquitocide *
4	BETA-AMYRIN-ACETATE	Root	--	--	--	*
Anticonvulsant * Antiinflammatory * Antinociceptive * Antioxidant *
47	BETA-SITOSTEROL	Root	--	--	--	*
Androgenic * Angiogenic * Anorexic Martindale's 28th Antiadenomic Merck 11th Edition Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Anticancer (Cervix) * Anticancer (Lung) * Antiedemic IC54=320 mg/kg orl * Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory * Antileukemic * Antilymphomic * Antimutagenic 250 ug/ml * Antiophidic 2.3 mg mus Economic & Medicinal Plant Research, 5: 363. Antioxidant IC44=10 uM * Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Antiprostaglandin 30 mg/day/12 wks * Antiprostatadenomic Merck 11th Edition Antiprostatitic 10-20 mg 3 x/day/orl man * Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103. Antitumor (Cervix) * Antitumor (Lung) * Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991. Apoptotic * Artemicide LC50=110 ppm Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155. Caspase-8-Inducer * Estrogenic * Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Hepatoprotective * Hypocholesterolemic 2-6 g/man/day/orl Martindale's 30th Hypocholesterolemic 9-3,330 mg/man/day/orl Martindale's 28th Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypolipidemic 2-6 g/day * Pesticide * Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990. Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Ulcerogenic 500 mg/kg ipr rat *
0	DESININE	Plant	--	--	--	*
0	EO	Root	1600.0	2250.0	-0.55	*
0	HEMIDESMOL	Root	--	--	--	*
0	HEMIDESTEROL	Root	--	--	--	*
0	HEXATRIACONTANE	Root	--	--	--	*
30	HYPEROSIDE	Flower	--	--	--	*
Aldose-Reductase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Analgesic * Antiaging * Antibacterial MIC=250-500 ug/ml Planta Medica, 57: A43, 1991. Anticancer * Anticapillary-Fragility Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Antidermatitic * Antielastase IC50=0.15 ug/ml * Antiflu Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980. Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Antiinflammatory 1/4 indomethacin Planta Medica, 57: A131, 1991. Antiischemic * Antinociceptive * Antioxidant IC50=4.6 uM * Antiradicular * Antitussive * Antiviral * Antiwrinkle * Calcium-Antagonist * cAMP-Inhibitor IC50=0.14 mg/ml Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Capillarifortificant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Capillarigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Cyclooxygenase-Activator 100 uM Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin. Diuretic * Hepatoprotective IC80=30 ug/ml Mayumi Ito (nee Someya), et al. 1990. Hepatoprotective Compounds from Canarium album and Euphorbia nematocypha. Chem. Pharm. Bull. 38(8): 2201-2203, 1990. Hypotensive ivn dog * Pesticide * Tissue-Thromboplastin-Inhibitor IC50=20.8 uM * Xanthine-Oxidase-Inhibitor *
0	ISOQUERCITIN	Flower	--	--	--	*
21	LUPEOL	Root	--	--	--	*
Antiangiogenic 30-50 ug/ml * AntiEBV * Antiedemic * Antiflu * Antihyperglycemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiinflammatory 1/3 indomethacin * Antilithic 25 mg/kg/day * Antimalarial IC50=46.8 ug/ml Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986. Antioxalate 25 mg/kg/day * Antioxidant 25 mg/kg/day * Antiperoxidant 25 mg/kg/day * Antiprostaglandin * Antirheumatic * Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiurethrotic * Antiviral * Cytotoxic 50-500 ppm * FPTase-Inhibitor IC50=65 ug/ml * Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * TOPO-2-Inhibitor IC50=10.4 uM *
2	LUPEOL-ACETATE	Root	--	--	--	*
Antihyperglycemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiulcer Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
0	LUPEOL-OCTACOSANOATE	Root	--	--	--	*
0	P-METHOXY-SALICYLIC-ALDEHYDE	Root	1280.0	1800.0	--	*
0	RESIN	Root	--	--	--	*
87	RUTIN	Flower	--	--	--	*
5-HT-Inhibitor * Aldehyde-Oxidase-Inhibitor IC27-52=10 uM * Aldose-Reductase-Inhibitor 4 ug/ml Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. Aldose-Reductase-Inhibitor 100 uM * Allelochemic * Antiaggregant ED50=33 nmol/kg iv * Antiallergic * Antiapoplectic * Antiatherogenic * Antiatherosclerotic * Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticancer * Anticapillary-Fragility 20-100 mg orl man Merck 7th Ed. Anticataract * Anticlastogen * Anticonvulsant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. AntiCVI 270 mg/man/day * Antidementia Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Antidiabetic Jin, G-Z., Yamagata, Y., and Tomita, K.-i. 1989. Structure of Rutin Pentamethanol. Chem. Pharm. Bull. 38(2): 297-300, 1990. Antiedemic 270 mg/day orl man * Antierythemic * Antifeedant * Antiglaucomic 60 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihematuric * Antihemorrhoidal * Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Antiherpetic Economic & Medicinal Plant Research, 5: 198. Antihistaminic * Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiinflammatory 20 mg/kg * Antimalarial IC50=>100 ug/ml Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986. Antimelanomic * Antimetastatic * Antimutagenic ID50=2-5 nM * Antinephritic * Antinociceptive * Antioxidant IC54=10 uM * Antioxidant IC28=30 ppm * Antioxidant IC50=120 uM * Antiperoxidant IC50=10-20 uM * Antiplatelet * Antiproliferant 50-75 uM/l * Antiprotozoal * Antipurpuric * Antiradicular 9 x quercetin * Antispasmodic * Antisunburn * Antithrombogenic EC50=500 nM * Antithyroid IC50=68 uM * Antitrypanosomic 100 mg/kg Planta Medica, 57: A44, 1991. Antitumor * Antitumor-Promoter * Antiulcer * Antivaricose * Antiviral * Apoptotic 75 uM/l * cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Capillariprotective Merck 11th Edition Catabolic * Chemopreventive * Cytoprotective IC50=3 uM * Estrogenic? Economic & Medicinal Plant Research, 6: 189. Hemostat * Hepatomagenic 20,000 ppm (diet) rat Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Hepatoprotective 20 mg/kg rat * Hypocholesterolemic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Hypotensive Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Immunomodulator * Insecticide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat IC95=4,000-8,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Lipoxygenase-Inhibitor IC75=2.5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Mutagenic Economic & Medicinal Plant Research, 6: 189. Myoprotective * Myorelaxant Economic & Medicinal Plant Research, 6: 189. Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. PAF-Inhibitor * Pesticide * Protisticide * Radioprotective * Sunscreen * Topoisomerase-II-Inhibitor IC50=1 ug/ml Bernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998. Vasodilator * Vasopressor *
5	SAPONINS	Root	--	--	--	*
Antihepatomic * Antimutagenic * Antitumor (Lung) * Antitumor (Ovary) * Immunomodulator *
0	TANNINS	Leaf	--	25000.0	-0.89	*

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Hemidesmus indicus (Asclepiadaceae)

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