Chelidonium majus | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Celandine

How used

Medicinal

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Activities: 249

Chemicals w/Activities: 20

All Chemicals: 43

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# Activity	Chemical Name	Part Filter by plant part	Low PPM	High PPM	StdDev	^*Reference
0	ALKALOIDS	Plant	2500.0	22000.0	0.17	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
5	ALLOCRYPTOPINE	Plant	--	--	--	*
Aldose-Reductase-Inhibitor IC50=27.9 uM rat Al-Khalil, S. 1996. Inhibition of Lens Alkaloids Reductase by Protopine Alkaloids. Saudi Pharm J, 4(1): 45-47. Analgesic * Antiarrhythmic Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. Antifibrillary Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. Soporific *
0	ALPHA-HOMOCHELIDONINE	Plant	--	--	--	*
130	BERBERINE	Plant	--	--	--	*
(+)-Inotropic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Abortifacient * Adrenolytic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Amebicide EC83=100 ug/ml orl rat Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Amebicide 200 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Analgesic * Anesthetic * Antiacetylcholinesterase * Antiacne Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiadrenergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiaggregant * Antialzheimeran * Antiamnesic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiangiogenic * Antiarrhythmic * Antiarthritic * Antibacillus MIC=200 ug/ml * Antibacterial 12.5-2,500 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antibacterial 100 mg/4x/day * Antibacterial MIC=6-630 ug/ml * Antibiotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticancer * Anticariogenic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antichlamydial * Anticholecystitic 5-20 mg/3x/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticholera 150 mg/man/day Martindale's 28th Anticirrhotic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticonjunctivitic 0.20% Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Anticonvulsant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antidiarrheic 100 mg/4x/day * Antidysenteric 100 mg/4x/day * Antiedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antiendotoxic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antienterotoxic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiesherichic * Antigiardial 10 mg/kg/day * Antiglaucomic * Antigonorrhea * Antihepatomic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antihepatotic * Antiherpetic * Antihistaminic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiinflammatory * Antiischemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antileishmanic 10 ug/ml * Antilipogenic IC63=10 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimalarial 0.14-0.36 ug/ml * Antimalarial 50 uM * Antimitotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antimuscarinic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antimyalgic * Antimycotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antineoplastic * Antinephritic * Antiperistaltic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antiphotooxidative * Antiplasmodial IC50=0.14-0.36 ug/ml * Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antipyretic 3 x aspirin * Antisalmonella * Antisecretory * Antiseptic 25 ug/ml * Antishigellic 12.5 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antispermigenic * Antistaphylococcic * Antistrep Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antisyphilitic * Antitrachomic 0.20% * Antitrypanosomic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antitubercular MIC=25 ug/ml * Antitumor (brain) IC91=150 ug/ml Werbach & Murray, 1994. Antiulcer * Antivaginitic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiviral Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Astringent * Bilirubinolytic * Calcium-Antagonist Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Candidicide * Cardiodepressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Cardiotonic * Carminative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cholagogue * Cholekinetic * Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Collyrium * COX-2-Inhibitor 100 ug/ml * Cyclooxygenase-Inhibitor * Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Digestive * Diuretic * Emetic * Fungicide 12.5-150 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Glaucomagenic * Hemostat * Hypocholesterolemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989. Hypoglycemic * Hypotensive * Immunostimulant * Lachrymatory Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Larvicide 9 ppm * Leucocytogenic * Lipase-Inhibitor Medline (post 1990 searches filed in my computer) Lipoxygenase-Inhibitor IC50=118 uM * Mutagenic * Mycobactericide MIC=25-50 ug/ml * Mydriatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Myocardiodepressant * Myorelaxant * Pesticide * Phototoxic 9 ppm * Plasmodicide IC50=0.14-0.36 ug/ml * Prostaglandin-Synthesis-Inhibitor 25 mg/kg ivn rbt Huang, C. G., Chu, Z. L., Yang, Z. M. 1991. Effect of Berberine on Synthesis of Platelet TXA2 and Plasma PGI2 in Rabbits. Chung-Kuo Yao Li Hsueh Pao, 12(6): 526-528. Protisticide IC50=0.14-0.36 ug/ml * Respiradepressant Martindale's 28th RNA-Depressant * RT-Inhibitor * Sedative * Stomachic * Topoisomerase-II-Inhibitor 2.5 uM Kobayashi, Y, Yamashita, Y., Fujii, N., Takaboshi, K., Kawakami, T., Kawamura, M., Mizukami, T., Nakano, H. 1995. Inhibitors of DNA Topoisomerase I and II Isolated From the Coptis Rhizomes. Planta Medica, 61: 414-418. Trichomonicide Martindale's 29th Trypanocide * Uterocontractant * Uterotonic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Vagostimulant man * Vasoconstrictor * Vasodilator 2 mg/kg cat * Vermifuge * Vibriofuge *
0	CHELAMIDINE	Plant	--	--	--	*
0	CHELAMINE	Plant	--	--	--	*
0	CHELERITINE	Root	--	--	--	*
33	CHELERYTHRINE	Plant	--	--	--	*
12-Lipoxygenase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. 5-Lipoxygenase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Analgesic * Antiacetylcholinesterase * Antiaggregant * Antibacterial Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiinflammatory 10 mg/kg orl rat (=5 mg indomethacin) Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Antiinflammatory * Antimitotic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Antineoplastic * Antiseptic * Antitumor Lewis and Elvin-Lewis, Medical Botany, ca 1977 Antitussive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiviral Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Candidicide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cytotoxic * DNA-Intercalator Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Fungicide 1-5 mg/ml * Gram(+)icide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Gram(-)icide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Hypertensive 3-5 mg/kg ivn * Hypotensive * Immunostimulant * Irritant Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Lipase-Inhibitor Medline (post 1990 searches filed in my computer) Molluscicide * Nematicide 50-100 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Occulotensive * Paralytic * Pesticide * Respirainhibitor * Tetanic * Topoisomerase-I-Inhibitor Fang, S. D., Wang, L. K., Hect, S. M. 1993. Inhibitors of DNA Topoisomerase I Isolated From the Roots of Zanthoxylum nitidum. J Org Chem, 58: 5025-5027.
0	CHELIDAMINE	Plant	--	--	--	*
2	CHELIDONIC-ACID	Plant	--	--	--	*
Antiwart Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill. Irritant Mitchell, J. and Rook, A.J. 1923. Botanical Dermatology: plants and plant products injurious to the skin. Vancouver: Greengrass, 1979. xiii, 787 p.: ill.
18	CHELIDONINE	Plant	--	--	--	*
Analgesic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antianaphylactic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antibacterial Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antibronchitic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiflu Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Antiherpetic * Antispasmodic * Antitussive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. CNS-Inhibitor * Cytotoxic Merck 11th Edition Diuretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Hypotensive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Lipase-Inhibitor Medline (post 1990 searches filed in my computer) Myodepressant Oriental Materia Medica (three volumes by Dr. Hsu and collaborators) Pesticide * Reverse-Transcriptase-Inhibitor Merck 11th Edition Sedative Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
0	CHELIDONIOL	Root	--	--	--	*
0	CHELILUTINE	Plant	--	--	--	*
3	CHELIRUBINE	Plant	--	--	--	*
Antibacterial * Molluscicide * Pesticide *
20	CHOLINE	Fruit	--	--	--	*
Antialzheimeran 5-16 g/man/day * Antichoreic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticirrhotic 6,000 mg/man/day * Anticystinuric * Antidementia * Antidiabetic * Antidyskinetic 150-200 mg/kg/man/day Martindale's 28th Antihomocysteine * Antimanic 15-30 g/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antinociceptive * Antisteatotic * Cardiodepressant * Cerebrotonic * Cholinergic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Hepatoprotective * Hypotensive * Ileorelaxant * Lipotropic * Memorigenic * Parasympathomimetic (1/1,000th acetylcholine) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
23	CITRIC-ACID	Plant	--	--	--	*
Allergenic * Alpha-Amylase-Inhibitor * Antiaphthic 20,000 ppm Martindale's 28th Antiatherosclerotic * Antibacterial * Anticalculic * Anticoagulant Merck 11th Edition Antileishmanic * Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antioxidant Synergist Merck 11th Edition Antiseborrheic * Antiseptic Martindale's 29th Antitubercular * Antitumor Economic & Medicinal Plant Research, 6: 235. Disinfectant Martindale's 29th FLavor FEMA 370-4,400 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Hemostat * Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Laxative? Lawrence Review of Natural Products, Sep-91. Litholytic Martindale's 29th Mycobactericide * Odontolytic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253. Refrigerant Martindale's 28th
3	COPTISINE	Plant	--	--	--	*
Antiinflammatory * Antitumor * Myocontractant *
0	CORYSAMINE	Plant	--	--	--	*
0	DIHYDROSANGUINARINE	Root	--	--	--	*
0	EO	Plant	--	130.0	-0.73	*

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^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Chelidonium majus (Papaveraceae)

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