Artemisia abrotanum | Plant | Dr. Duke's Phytochemical and Ethnobotanical Databases

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Common name(s)

Southernwood

How used

Medicinal

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Activities: 224

Chemicals w/Activities: 13

All Chemicals: 18

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# Activity	Chemical Name	Part	Low PPM	High PPM	StdDev	^*Reference
2	ABROTINE	Plant	20000.0	30000.0	--	*
Insectifuge Grainge, M. and Ahmed, S., Handbook of Plants with Pest-Control Properties, John Wiley & Sons, New York, NY, 1988, 470. Pesticide *
11	ADENINE	Plant	--	--	--	*
Antianemic 1.5 g/day Martindale's 28th Antigranulocytopenic * Antiviral * CNS-Stimulant * Diuretic * Hyperuricemic Martindale's 28th Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Lithogenic * Myocardiotonic * Pesticide * Vasodilator *
28	ADENOSINE	Plant	--	--	--	*
Analgesic * Antiaggregant * Antiarrhythmic Merck 11th Edition Antidiuretic LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Antiendotoxic 500 mg/kg ipr mus Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006. Antihypertensive LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Antiinsomniac * Antilipolytic * Antispasmodic * Antitachycardic 50-250 ug/kg/ivn Martindale's 29th Anxiolytic * Arteriodilator * Glucogonogenic LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Hypocholesterolemic LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Hypoglycemic * Hypotensive LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Immunomodulator * Insulinic * Laxative * Lipolytic LAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp. Myorelaxant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. PAF-Inhibitor 0.024 ug/ml * PAF-Inhibitor IC50=90 nM * Pyrogenic 0.09 mg/kg ivn hmn Conradson, T. B. G., Dixon, C. M. S., Clarke, B., Barnes, P. J. 1987. Cardiovascular Effects of Infused Adenosine in Man: Potentiation by Dipyridamole. Acta Physiol Scand, 129(3): 387-391. Respirastimulant Martindale's 29th Secretomotor * Sedative Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Vasodilator *
0	ARTEMISITIN	Plant	--	--	--	*
102	CAFFEIC-ACID	Plant	--	--	--	*
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity) Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. Allergenic * Analgesic * Antiadenoviral Economic & Medicinal Plant Research, 5: 207. Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiaging * Antiatherogenic * Antibacterial * Anticancer * Anticarcinogenic Economic & Medicinal Plant Research, 6: 189. Antidepressant * Antiedemic Economic & Medicinal Plant Research, 6: 189. Antielastase IC50=93 um/l * Antielastase IC50=86 ug/ml (475 uM) * Antiescherichic * Antiflu Economic & Medicinal Plant Research, 5: 207. Antigonadotropic Jim Duke's personal files. Antihemolytic 25 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antihepatoadenomic 200 ppm diet orl mus * Antihepatotoxic * Antiherpetic 50 ug/ml * Antiherpetic EC50=>50 ug/ml * Antihistaminic * AntiHIV EC50=200 ug/ml * Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189. Antihyperthyroid * Antiinflammatory * AntiLegionella * Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antileukotriene * Antimelanogenic * Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18. Antiophidic * Antioxidant 1/3 quercetin * Antioxidant 1/2 BHA * Antioxidant 30 mM * Antioxidant 1.3 x Vit. E * Antioxidant 50 uM * Antioxidant IC57=30 ppm * Antiperoxidant IC50=44 uM Planta Medica, 57: A54, 1991. Antiperoxidant IC35=200 ug/ml * Antiperoxidant IC85=100 ug/ml * Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46. Antiprostaglandin * Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiradicular 1/3 quercetin * Antiradicular 30 mM * Antiradicular IC50=32-35 uM * Antiseptic * Antispasmodic EC50=3.4-15 uM Phytotherapy Research, 4: 73. Antistaphylococcic * Antistomatitic Economic & Medicinal Plant Research, 5: 207. Antisunburn * Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69. Antithyroid Jim Duke's personal files. Antitumor 200 ppm diet orl mus * Antitumor (Skin) * Antitumor-Promoter IC42=10 uM Cancer Research, 48: 5941. Antiulcerogenic * Antivaccinia Economic & Medicinal Plant Research, 5: 207. Antiviral IC50=62.5 ug/ml * Anxiolytic * Calcium-Antagonist IC50=1.2 uM rbt * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Carcinogenic 2% (diet) * Chemopreventive * Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Co-carcinogenic * Collagen-Sparing * COX-2-Inhibitor IC32=100 uM * Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Cytotoxic TC50=200 ug/ml * Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. DNA-Protective * Fungicide MIC=0.4 mg/ml * Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol) * Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210. Hepatotropic * Histamine-Inhibitor * Immunostimulant * Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Leukotriene-Inhibitor * Lipoxygenase-Inhibitor IC50=62-148 uM * Lipoxygenase-Inhibitor IC27=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Lyase-Inhibitor IC50=94-164 uM * Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Pesticide * Prooxidant * Prostaglandigenic * Sedative 500 mg * Sunscreen IC50=2.5 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC91=5 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Sunscreen IC98=25 mg/l Lazarova, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993. Tumorigenic Jim Duke's personal files. Vulnerary Xanthine-Oxidase-Inhibitor IC50=39.21 uM Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
0	CALYCANTHOSIDE	Plant	--	--	--	*
77	CHLOROGENIC-ACID	Plant	--	--	--	*
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity) Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345. Allelochemic * Allergenic * Analgesic * Antiatherosclerotic * Antibacterial * Anticancer (Colon) * Anticancer (Forestomach) * Anticancer (Liver) * Anticancer (Skin) * Anticarcinogenic * Antidiabetic * AntiEBV Economic & Medicinal Plant Research, 6: 189. Antifeedant * Antigenotoxic * Antigonadotropic Jim Duke's personal files. Antihemolytic 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antihepatotoxic * Antiherpetic Economic & Medicinal Plant Research, 5: 194. Antihistaminic * AntiHIV Economic & Medicinal Plant Research, 6: 189. Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189. Antihyperthyroid * Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. AntiLegionella * Antileukotriene * Antimelanogenic * Antimutagenic * Antinitrosaminic * Antioxidant IC50=54.2 uM * Antioxidant IC53=200 ppm Huang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21. Antioxidant IC80=12 uM * Antiperoxidant IC50=36 uM Planta Medica, 57: A54, 1991. Antipolio Jim Duke's personal files. Antiradicular 10 uM Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994. Antiradicular 9 x quercetin * Antiseptic * Antisunburn * Antithyroid Jim Duke's personal files. Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antitumor (Colon) * Antitumor (Forestomach) * Antitumor (Liver) * Antitumor (Skin) * Antitumor-Promoter IC25=10 uM * Antiulcer Economic & Medicinal Plant Research, 6: 189. Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. Autotoxic * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cardioprotective * Chemopreventive * Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Clastogenic Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808. CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. CNS-Stimulant 1/6 Caffeine * Collagen-Sparing * Diuretic * Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Histamine-Inhibitor * Hypoglycemic * Immunostimulant * Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994. Interferonogenic Economic & Medicinal Plant Research, 1: 124. Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Leukotriene-Inhibitor * Lipoxygenase-Inhibitor IC23=5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25. NO-Genic * Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19. Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Pesticide * Sunscreen * Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Vulnerary *
20	CHOLINE	Plant	--	--	--	*
Antialzheimeran 5-16 g/man/day * Antichoreic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp. Anticirrhotic 6,000 mg/man/day * Anticystinuric * Antidementia * Antidiabetic * Antidyskinetic 150-200 mg/kg/man/day Martindale's 28th Antihomocysteine * Antimanic 15-30 g/man/day/orl Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Antinociceptive * Antisteatotic * Cardiodepressant * Cerebrotonic * Cholinergic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp. Hepatoprotective * Hypotensive * Ileorelaxant * Lipotropic * Memorigenic * Parasympathomimetic (1/1,000th acetylcholine) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
0	EO	Plant	1800.0	21000.0	0.86	*
1	GUANINE	Plant	--	--	--	*
Essential Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
5	ISOFRAXIDIN	Plant	--	--	--	*
Aldose-Reductase-Inhibitor 10 ug/ml cow (weak activity, 18% inhibition) Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Antileukemic ED50=1.7 * Antimalarial IC50=7.95 ug/ml * Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Choleretic *
0	QUEBRACHITOL	Plant	--	--	--	*
87	RUTIN	Plant	--	--	--	*
5-HT-Inhibitor * Aldehyde-Oxidase-Inhibitor IC27-52=10 uM * Aldose-Reductase-Inhibitor 100 uM * Aldose-Reductase-Inhibitor 4 ug/ml Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110. Allelochemic * Antiaggregant ED50=33 nmol/kg iv * Antiallergic * Antiapoplectic * Antiatherogenic * Antiatherosclerotic * Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Anticancer * Anticapillary-Fragility 20-100 mg orl man Merck 7th Ed. Anticataract * Anticlastogen * Anticonvulsant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. AntiCVI 270 mg/man/day * Antidementia Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp. Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Antidiabetic Jin, G-Z., Yamagata, Y., and Tomita, K.-i. 1989. Structure of Rutin Pentamethanol. Chem. Pharm. Bull. 38(2): 297-300, 1990. Antiedemic 270 mg/day orl man * Antierythemic * Antifeedant * Antiglaucomic 60 mg/day Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp. Antihematuric * Antihemorrhoidal * Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Antiherpetic Economic & Medicinal Plant Research, 5: 198. Antihistaminic * Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Antiinflammatory 20 mg/kg * Antimalarial IC50=>100 ug/ml Khalid, S.A., Farouk, A., Geary*, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum. Journal of Ethnopharmacology, 15: 201-209, 1986. Antimelanomic * Antimetastatic * Antimutagenic ID50=2-5 nM * Antinephritic * Antinociceptive * Antioxidant IC54=10 uM * Antioxidant IC28=30 ppm * Antioxidant IC50=120 uM * Antiperoxidant IC50=10-20 uM * Antiplatelet * Antiproliferant 50-75 uM/l * Antiprotozoal * Antipurpuric * Antiradicular 9 x quercetin * Antispasmodic * Antisunburn * Antithrombogenic EC50=500 nM * Antithyroid IC50=68 uM * Antitrypanosomic 100 mg/kg Planta Medica, 57: A44, 1991. Antitumor * Antitumor-Promoter * Antiulcer * Antivaricose * Antiviral * Apoptotic 75 uM/l * cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf). Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Capillariprotective Merck 11th Edition Catabolic * Chemopreventive * Cytoprotective IC50=3 uM * Estrogenic? Economic & Medicinal Plant Research, 6: 189. Hemostat * Hepatomagenic 20,000 ppm (diet) rat Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp. Hepatoprotective 20 mg/kg rat * Hypocholesterolemic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Hypotensive Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp. Immunomodulator * Insecticide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp. Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Larvistat IC95=4,000-8,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Lipoxygenase-Inhibitor IC75=2.5 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690. Mutagenic Economic & Medicinal Plant Research, 6: 189. Myoprotective * Myorelaxant Economic & Medicinal Plant Research, 6: 189. Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. PAF-Inhibitor * Pesticide * Protisticide * Radioprotective * Sunscreen * Topoisomerase-II-Inhibitor IC50=1 ug/ml Bernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998. Vasodilator * Vasopressor *
44	SCOPOLETIN	Plant	--	--	--	*
Aldose-Reductase-Inhibitor IC50=6.2 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Allelochemic IC89=2 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Analgesic * Anesthetic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antiadrenergic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antiaflatoxin IC50=65 uM * Antiaflatoxin 11.4 ppm * Antiarrhythmic * Antiasthmatic * Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antibronchoconstrictor * Anticholinergic * Antiedemic * Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990. Antihepatotoxic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Antiinflammatory ED 1-10 ug/ear * Antileukotrienogenic * Antimutagenic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh. Antioxidant * Antiproliferant * Antiprostaglandin * Antiseptic * Antispasmodic * Antitumor 2.9 ug/ml * Apoptotic * Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp. Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. CNS-Depressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. CNS-Stimulant Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp. Cytotoxic * Fungicide 2 mM * Hepatoprotective Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Herbicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Hypoglycemic Economic & Medicinal Plant Research, 6: 165 Hypotensive * MAO-Inhibitor * Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp. Myorelaxant * Pesticide * Phytoalexin * Phytohormonal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Uterosedative Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
3	SCOPOLIN	Plant	--	--	--	*
Anticholinergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. CNS-Depressant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
35	TANNIN	Plant	--	--	--	*
Anthelmintic * Antibacterial * Anticancer * Anticariogenic * Antidiarrheic * Antidysenteric * Antihepatotoxic * AntiHIV * Antihypertensive * Antilipolytic * Antimutagenic * Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antiophidic Economic & Medicinal Plant Research, 5: 363. Antioxidant IC50=1.44 ug/ml * Antioxidant 1/3 quercetin * Antiradicular 1/3 quercetin * Antiradicular 500 mg/kg/day orl mus Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Antitumor * Antitumor-Promoter * Antiulcer * Antiviral * Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14. Carcinogenic * Chelator * Cyclooxygenase-Inhibitor * Glucosyl-Transferase-Inhibitor * Hepatoprotective * Immunosuppressant * Lipoxygenase-Inhibitor * MAO-Inhibitor * Ornithine-Decarboxylase-Inhibitor * Pesticide * Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990. Xanthine-Oxidase-Inhibitor *
22	UMBELLIFERONE	Plant	--	--	--	*
Aldose-Reductase-Inhibitor IC50=4.8 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387 Allelochemic IC94=2 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp. Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. Antiedemic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. Antihistaminic * Antiinflammatory * Antimitotic 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526. Antimutagenic Economic & Medicinal Plant Research, 6: 235. Antiprostaglandin * Antiseptic * Antispasmodic * Antistaphylococcic * Cancer-Preventive 5-25 ug/ml Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526. Candidicide * Choleretic * Fungicide Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. Lipoxygenase-Inhibitor * Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Pesticide * Photoactive * Sunscreen Merck 11th Edition Xanthine-Oxidase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
0	URIC-ACID	Plant	--	--	--	*

^*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

Plant Artemisia abrotanum (Asteraceae)

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