Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
NADH-Ubiquinone-Oxidoreductase-Inhibitor	not available	Duke, 1992 *
Natriuretic	not available	Duke, 1992 *
Ornithine-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Peroxidase-Inhibitor	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide	not available	Duke, 1992 *
Phytoalexin	not available	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Pituitary-sensitizer	not available	Medline (post 1990 searches filed in my computer)
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Quinone-Reductase-Inducer	IC50=4.6 ug/ml	Duke, 1992 *
Topoisomerase-I-Inhibitor	IC50=250 ppm	Duke, 1992 *
Topoisomerase-I-Inhibitor	1-10 ug/ml	Okura, A., Arakawa, H., Oka, H., Yoshinari, T., Monden, Y. 1988. Effect of Genistein on Topoisomerase Activity and on the Growth of [VAL 12]HA-RAS-Transformed NIH 3T3 Cells. Biochem Biophys Res Commun, 157: 183-189.
Topoisomerase-II-Inhibitor	20 uM	Markovits, J., et al. 1989. Inhibitory Effects of the Tyrosine Kinase Inhibitor Genistein on Mammalian DNA Topoisomerase II. Cancer Research, 49: 5111-5117.
Topoisomerase-II-Inhibitor	IC50=1-150 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	2-7.5 ug/ml	Duke, 1992 *
Topoisomerase-II-Inhibitor	IC50=30 ug/ml	Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Topoisomerase-II-Poison	not available	Journal of Medicinal Food 2: 167.1999.
Trypanosomastat	not available	Medline (post 1990 searches filed in my computer)
Tyrosine-Kinase-Inhibitor	not available	Duke, 1992 *
Uterotrophic	EC50=0.1-25 uM/l	Duke, 1992 *
Uterotrophic	ED50=0.5 mg/kg	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Canavalia rosea	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Canavalia sericea	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Canavalia virosa	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Centrosema pascuorum	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Centrosema plumieri	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Centrosema sagittatum	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Centrosema schiedianum	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Chamaecytisus albus	Leaf	not available	not available	not available	Duke, 1992 *
Chamaecytisus eriocarpus	Leaf	not available	not available	not available	Duke, 1992 *
Chamaecytisus hirsutus	Leaf	not available	not available	not available	Duke, 1992 *
Chamaecytisus ratisbonensis	Leaf	not available	not available	not available	Duke, 1992 *
Chamaecytisus smyrnaeus	Leaf	not available	not available	not available	Duke, 1992 *
Chamaecytisus supinus	Leaf	not available	not available	not available	Duke, 1992 *
Chamaespartium sagittale	Leaf	not available	not available	not available	Duke, 1992 *
Chamaespartium tridentatum	Leaf	not available	not available	not available	Duke, 1992 *
Chronanthus biflorus	Leaf	not available	not available	not available	Duke, 1992 *
Cicer arietinum	Seed	not available	46.1	-0.3	Kaufman,PB,Duke,JA,Brielmann,H,Boik,J and Hoyt,JE. 1997. A Comparative Survey of Leguminous Plants as Sources of the Isoflavones Genistein and Daidzein: Implications For Human Nutrition and Health. Journal of Alternative & Complementary Medicine 3(1):7-12
Clitoria falcata	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Clitoria ternatea	Leaf Diffusate	not available	25.0	1.6	Duke, 1992 *
Cologana broussonetii	Leaf Diffusate	not available	not available	not available	Duke, 1992 *