Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
NADH-Ubiquinone-Oxidoreductase-Inhibitor	not available	Duke, 1992 *
Natriuretic	not available	Duke, 1992 *
Ornithine-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Peroxidase-Inhibitor	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide	not available	Duke, 1992 *
Phytoalexin	not available	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Pituitary-sensitizer	not available	Medline (post 1990 searches filed in my computer)
PTK-Inhibitor	10-100 uM	Duke, 1992 *
Quinone-Reductase-Inducer	IC50=4.6 ug/ml	Duke, 1992 *
Topoisomerase-I-Inhibitor	IC50=250 ppm	Duke, 1992 *
Topoisomerase-I-Inhibitor	1-10 ug/ml	Okura, A., Arakawa, H., Oka, H., Yoshinari, T., Monden, Y. 1988. Effect of Genistein on Topoisomerase Activity and on the Growth of [VAL 12]HA-RAS-Transformed NIH 3T3 Cells. Biochem Biophys Res Commun, 157: 183-189.
Topoisomerase-II-Inhibitor	IC50=1-150 uM	Duke, 1992 *
Topoisomerase-II-Inhibitor	2-7.5 ug/ml	Duke, 1992 *
Topoisomerase-II-Inhibitor	IC50=30 ug/ml	Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
Topoisomerase-II-Inhibitor	20 uM	Markovits, J., et al. 1989. Inhibitory Effects of the Tyrosine Kinase Inhibitor Genistein on Mammalian DNA Topoisomerase II. Cancer Research, 49: 5111-5117.
Topoisomerase-II-Poison	not available	Journal of Medicinal Food 2: 167.1999.
Trypanosomastat	not available	Medline (post 1990 searches filed in my computer)
Tyrosine-Kinase-Inhibitor	not available	Duke, 1992 *
Uterotrophic	EC50=0.1-25 uM/l	Duke, 1992 *
Uterotrophic	ED50=0.5 mg/kg	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Crotalaria juncea	Leaf	not available	not available	not available	Duke, 1992 *
Cytisus ardoini	Leaf	not available	not available	not available	Duke, 1992 *
Cytisus ingramii	Leaf	not available	not available	not available	Duke, 1992 *
Cytisus multiflorus	Leaf	not available	not available	not available	Duke, 1992 *
Cytisus scoparius	Flower	not available	not available	not available	Duke, 1992 *
Cytisus striatus	Leaf	not available	not available	not available	Duke, 1992 *
Cytisus tribracteolatus	Leaf	not available	not available	not available	Duke, 1992 *
Desmodium gangeticum	Leaf Diffusate	not available	8.0	-0.3	Duke, 1992 *
Dioclea glycinoides	Leaf Diffusate	not available	15.0	0.5	Duke, 1992 *
Dipogon lignosus	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Dolichos biflorus	Leaf	not available	not available	not available	Duke, 1992 *
Dunbaria villosa	Leaf Diffusate	not available	13.0	0.3	Duke, 1992 *
Echinospartium horridum	Leaf	not available	not available	not available	Duke, 1992 *
Erinacea anthyllis	Leaf	not available	not available	not available	Duke, 1992 *
Eriosema glomeratum	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Eriosema nutans	Leaf Diffusate	not available	7.0	-0.4	Duke, 1992 *
Eriosema psoraleoides	Leaf Diffusate	not available	6.0	-0.5	Duke, 1992 *
Erythrina crista-galli	Bark	not available	not available	not available	Duke, 1992 *
Erythrina sp	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Flemingia strobilifera	Leaf Diffusate	not available	18.0	0.8	Duke, 1992 *