Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Calcium-Antagonist	50 uM gpg	Duke, 1992 *
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective	not available	Journal of Medicinal Food 2: 163.1999.
Catechol-O-Methyltransferase-Inhibitor	not available	Duke, 1992 *
Cytotoxic	IC89=10 ug/ml	Planta Medica, 57: A113, 1991.
Cytotoxic	>50 ug/ml (185 uM)	Medline (post 1990 searches filed in my computer)
DOPA-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Estrogen-Agonist	0.1-1 uM/l	Journal of Medicinal Food 2: 139.1999.
Estrogenic	EC50=0.1-25 uM/l	Duke, 1992 *
Flatulent	not available	Duke, 1992 *
Fungicide	2.5 mM	Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995.
Fungicide	ED50=50->100	Duke, 1992 *
Fungistat	IC34=200 uM	Duke, 1992 *
Histidine-Kinase-Inhibitor	IC50=110 uM	Medline (post 1990 searches filed in my computer)
Hypocholesterolemic	ED50=0.5 mg/kg	Duke, 1992 *
Immunostimulant	2-20 mg/kg orl mus	Duke, 1992 *
Lipase-Inhibitor	not available	Duke, 1992 *
MAO-Inhibitor	IC50=60-140 uM	Duke, 1992 *
MAO-Inhibitor	IC50=95	Duke, 1992 *
MDR-Inhibitor	200 uM	Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Piptanthus nanus	Shoot	not available	not available	not available	Duke, 1992 *
Piptanthus nepalensis	Shoot	not available	not available	not available	Duke, 1992 *
Pisum sativum	Seed	not available	45.8	-0.3	Kaufman,PB,Duke,JA,Brielmann,H,Boik,J and Hoyt,JE. 1997. A Comparative Survey of Leguminous Plants as Sources of the Isoflavones Genistein and Daidzein: Implications For Human Nutrition and Health. Journal of Alternative & Complementary Medicine 3(1):7-12
Pisum sativum	Shoot	not available	not available	not available	Duke, 1992 *
Podocarpus spicatus	Wood	not available	not available	not available	Duke, 1992 *
Prunus aequinoctialis	Wood	not available	not available	not available	Duke, 1992 *
Prunus avium	Wood	not available	not available	not available	Duke, 1992 *
Prunus cerasus	Fruit	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Prunus mahaleb	Wood	not available	not available	not available	Duke, 1992 *
Prunus maximowiczii	Wood	not available	not available	not available	Duke, 1992 *
Prunus nipponica	Wood	not available	not available	not available	Duke, 1992 *
Prunus spp	Wood	not available	not available	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Prunus verecunda	Wood	not available	not available	not available	Duke, 1992 *
Pseudeminia comosa	Leaf Diffusate	not available	4.0	-0.7	Duke, 1992 *
Pseudoeriosema borianii	Leaf Diffusate	not available	20.0	1.1	Duke, 1992 *
Pseudovigna argentea	Leaf Diffusate	not available	8.0	-0.3	Duke, 1992 *
Psoralea corylifolia	Seed	not available	1528.0	-0.3	Duke, 1992 *
Pterocarpus angolensis	Wood	not available	not available	not available	Duke, 1992 *
Pueraria montana	Leaf Diffusate	not available	3.0	-0.8	Duke, 1992 *
Pueraria montana	Stem	not available	not available	not available	Duke, 1992 *