Chemical GENISTEIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

GENISTEIN

Ubiquitous

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Calcium-Antagonist	50 uM gpg	Duke, 1992 *
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective	not available	Journal of Medicinal Food 2: 163.1999.
Catechol-O-Methyltransferase-Inhibitor	not available	Duke, 1992 *
Cytotoxic	>50 ug/ml (185 uM)	Medline (post 1990 searches filed in my computer)
Cytotoxic	IC89=10 ug/ml	Planta Medica, 57: A113, 1991.
DOPA-Decarboxylase-Inhibitor	not available	Duke, 1992 *
Estrogen-Agonist	0.1-1 uM/l	Journal of Medicinal Food 2: 139.1999.
Estrogenic	EC50=0.1-25 uM/l	Duke, 1992 *
Flatulent	not available	Duke, 1992 *
Fungicide	2.5 mM	Geibel, M. 1994. Sensitivity of the Fungus Cytospora persoonii to the Flavonoids of Prunus cerasus. Phytochemistry. 38(3): 599-601. 1995.
Fungicide	ED50=50->100	Duke, 1992 *
Fungistat	IC34=200 uM	Duke, 1992 *
Histidine-Kinase-Inhibitor	IC50=110 uM	Medline (post 1990 searches filed in my computer)
Hypocholesterolemic	ED50=0.5 mg/kg	Duke, 1992 *
Immunostimulant	2-20 mg/kg orl mus	Duke, 1992 *
Lipase-Inhibitor	not available	Duke, 1992 *
MAO-Inhibitor	IC50=60-140 uM	Duke, 1992 *
MAO-Inhibitor	IC50=95	Duke, 1992 *
MDR-Inhibitor	200 uM	Castro, A. F., Altenberg, G. A. 1997. Inhibition of Drug Transport by Genistein in Multidrug-Resistant Cell Expressing P-Glycoprotein. Biochem Pharmacol, 53(1): 89-93.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Hardenbergia violacea	Leaf Diffusate	not available	8.0	-0.3	Duke, 1992 *
Kennedia coccinea	Leaf Diffusate	not available	49.0	4.3	Duke, 1992 *
Kennedia nigricans	Leaf Diffusate	not available	24.0	1.5	Duke, 1992 *
Kennedia procurrens	Leaf Diffusate	not available	33.0	2.5	Duke, 1992 *
Kennedia rubicunda	Leaf Diffusate	not available	25.0	1.6	Duke, 1992 *
Laburnum alpinum	Leaf	not available	not available	not available	Duke, 1992 *
Laburnum anagyroides	Leaf	not available	not available	not available	Duke, 1992 *
Lembotropis emerifolia	Leaf	not available	not available	not available	Duke, 1992 *
Lens culinaris	Seed	not available	25.0	-0.3	Kaufman,PB,Duke,JA,Brielmann,H,Boik,J and Hoyt,JE. 1997. A Comparative Survey of Leguminous Plants as Sources of the Isoflavones Genistein and Daidzein: Implications For Human Nutrition and Health. Journal of Alternative & Complementary Medicine 3(1):7-12
Lespedeza cyrtobotrya	Wood	not available	not available	not available	Duke, 1992 *
Lupinus albus	Hypocotyl	not available	not available	not available	Duke, 1992 *
Lupinus luteus	Leaf	not available	not available	not available	Duke, 1992 *
Lupinus perennis	Plant	not available	not available	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lygos monosperma	Leaf	not available	not available	not available	Duke, 1992 *
Lygos raetum	Leaf	not available	not available	not available	Duke, 1992 *
Maackia amurensis	Wood	not available	not available	not available	Duke, 1992 *
Macroptylium atropurpureum	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Macroptylium bracteatum	Leaf Diffusate	not available	5.0	-0.6	Duke, 1992 *
Macroptylium lathyroides	Leaf Diffusate	not available	not available	not available	Duke, 1992 *
Macroptylium martii	Leaf Diffusate	not available	not available	not available	Duke, 1992 *