Chemical EUGENOL | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

EUGENOL

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=2,680 (orl rat)	Jim Duke's personal files.
LD50=3,000 (orl mus)
LDlo=500 (orl rat)
ADI=2.5 mg/kg	Martindale's 28th

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Motor-Depressant	not available	Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide	MLC=2,000 ug/ml	Shoyakugaku Zasshi, 44: 183.
Neurotoxic	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery	not available	Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide	not available	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	IC50=9.2 uM	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	1 mM rbt	Chen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Sedative	not available	Duke, 1992 *
Termiticide	LD100=5 mg/g	Duke, 1992 *
Trichomonicide	LD100=300 ug/ml	Duke, 1992 *
Trichomonistat	IC50=10 ug/ml	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer	not available	Lawrence Review of Natural Products, Dec-93.
Ulcerogenic	not available	Phytotherapy Research, 4: 93.
Varroacide	not available	Duke, 1992 *
Vasodilator	not available	Duke, 1992 *
Vermifuge	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Thymus funkii	Shoot	not available	not available	not available	Vila, R., et al. 1995. Composition and study of the variability of the essential oil of Thymus funkii Cousson. Flav. & Fragr. J. 10(6): 379-383.
Thymus vulgaris	Plant	not available	not available	not available	Stitt, Paul. Why George should eat broccoli.
Tilia sp.	Flower	not available	not available	not available	Duke, 1992 *
Trifolium pratense	Flower	not available	not available	not available	Duke, 1992 *
Umbellularia californica	Plant	10.0	40.0	-0.6	Duke, 1992 *
Vaccinium corymbosum	Fruit	not available	0.0	-0.7	Duke, 1992 *
Vaccinium macrocarpon	Fruit	not available	not available	not available	Duke, 1992 *
Vaccinium myrtillus	Fruit Juice	not available	0.0	not available	Duke, 1992 *
Vanilla planifolia	Fruit	not available	not available	not available	Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Viola odorata	Flower	147.0	357.0	-0.4	Duke, 1992 *
Viola odorata	Leaf	not available	not available	not available	Duke, 1992 *
Zea mays	Seed	not available	not available	not available	Duke, 1992 *
Zingiber officinale	Rhizome Essent. Oil	not available	not available	not available	Duke, 1992 *