Chemical EUGENOL | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

EUGENOL

Ubiquitous

List of known dosages
Dosage	Reference
LD50=2,680 (orl rat)	Jim Duke's personal files.
LD50=3,000 (orl mus)
LDlo=500 (orl rat)
ADI=2.5 mg/kg	Martindale's 28th

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Motor-Depressant	not available	Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide	MLC=2,000 ug/ml	Shoyakugaku Zasshi, 44: 183.
Neurotoxic	not available	R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery	not available	Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide	not available	Duke, 1992 *
Prostaglandin-Synthesis-Inhibitor	1 mM rbt	Chen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Prostaglandin-Synthesis-Inhibitor	IC50=9.2 uM	Duke, 1992 *
Sedative	not available	Duke, 1992 *
Termiticide	LD100=5 mg/g	Duke, 1992 *
Trichomonicide	LD100=300 ug/ml	Duke, 1992 *
Trichomonistat	IC50=10 ug/ml	Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer	not available	Lawrence Review of Natural Products, Dec-93.
Ulcerogenic	not available	Phytotherapy Research, 4: 93.
Varroacide	not available	Duke, 1992 *
Vasodilator	not available	Duke, 1992 *
Vermifuge	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Rosa gallica	Flower	2.0	4.0	-0.4	Duke, 1992 *
Rosmarinus officinalis	Shoot	not available	0.5	-0.5	Tucker, A. O. and Maciarello, M. J. 1998. The essential oils of some rosemary cultivars. Flavor and Fragrance Journal, 1: 137-142. 1986.
Santalum album	Wood	not available	not available	not available	Duke, 1992 *
Sassafras albidum	Root	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Scutellaria baicalensis	Root Essent. Oil	not available	not available	not available	Duke, 1992 *
Stevia rebaudiana	Flower	not available	not available	not available	Kinghorn, A. D. (Ed.) 2002. Medicinal and Aromatic Plants - Industrial Profiles. Stevia. The genus Stevia. Taylor & Francis. New York, NY. 211 pp.
Stevia rebaudiana	Leaf	not available	not available	not available	Kinghorn, A. D. (Ed.) 2002. Medicinal and Aromatic Plants - Industrial Profiles. Stevia. The genus Stevia. Taylor & Francis. New York, NY. 211 pp.
Syzygium aromaticum	Flower	108655.0	180000.0	2.6	Duke, 1992 *
Syzygium aromaticum	Leaf	7920.0	26400.0	2.3	Duke, 1992 *
Syzygium aromaticum	Bark	not available	not available	not available	Duke, 1992 *
Syzygium aromaticum	Stem	36000.0	57000.0	1.0	Duke, 1992 *
Syzygium aromaticum	Leaf Essent. Oil	not available	not available	not available	Duke, 1992 *
Syzygium aromaticum	Fruit	not available	not available	not available	Duke, 1992 *
Syzygium aromaticum	Essential Oil	61000.0	627000.0	1.1	Duke, 1992 *
Syzygium aromaticum	Bulb	not available	not available	not available	Duke, 1992 *
Tanacetum parthenium	Fruit Essent. Oil	not available	1000.0	not available	Duke, 1992 *
Tanacetum parthenium	Essential Oil	not available	not available	not available	Duke, 1992 *
Thymus capitatus	Shoot	not available	21.0	-0.5	Biondi, D., Cianci, P., Geraci, C. and Ruberto, G. 1993. Antimicrobial Activity and Chemical Composition of Essential Oils from Sicilian Aromatic Plants. Flav. & Frag. J. 8: 331-7.
Thymus cilicicus	Shoot	not available	0.1	-0.5	Tumen, G., Koyuncu, M., Kirimer, N., and Baser, K.H.C. 1994. Composition of the Essential Oil of Thymus cilicicus Boiss. & Bal. J. Ess. Oil Res. 6: 97-8.
Thymus funkii	Shoot	not available	5.0	-0.5	Vila, R., et al. 1995. Composition and study of the variability of the essential oil of Thymus funkii Cousson. Flav. & Fragr. J. 10(6): 379-383.