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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. EUGENOL

EUGENOL

Chemical ID
EUGENOL
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,680 (orl rat) Jim Duke's personal files.
LD50=3,000 (orl mus)
LDlo=500 (orl rat)
ADI=2.5 mg/kg Martindale's 28th

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=2,000 ug/ml Shoyakugaku Zasshi, 44: 183.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide *
Prostaglandin-Synthesis-Inhibitor IC50=9.2 uM *
Prostaglandin-Synthesis-Inhibitor 1 mM rbt Chen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Sedative *
Termiticide LD100=5 mg/g *
Trichomonicide LD100=300 ug/ml *
Trichomonistat IC50=10 ug/ml Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer Lawrence Review of Natural Products, Dec-93.
Ulcerogenic Phytotherapy Research, 4: 93.
Varroacide *
Vasodilator *
Vermifuge *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Ocimum sanctum Leaf 4200.0 4970.0 -0.2 Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Ocimum sp Plant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ocimum suave Shoot 110.0 2860.0 1.8 J. Nat. Prod. 44: 308.
Ocimum tenuiflorum Leaf 45.0 5580.0 -0.2 *
Ocimum tenuiflorum Stem 20.0 100.0 -1.0 *
Ocimum tenuiflorum Inflorescence 0.0 *
Oenanthe javanica Shoot *
Origanum majorana Plant 200.0 2000.0 0.5 *
Origanum majorana Leaf Essent. Oil 255000.0 -0.3 *
Origanum minutiflorum Shoot 55.0 125.0 -0.4 Baser, K.H.C., Tumen, G., Sezik, E. 1991. The Essential Oil of Origanum minutiflorum O. Schwarz and P.H. Davis. J. Ess. Oil Res. 3: 445-446.
Origanum onites Shoot 0.0 -0.5 Biondi, D., Cianci, P., Geraci, C. and Ruberto, G. 1993. Antimicrobial Activity and Chemical Composition of Essential Oils from Sicilian Aromatic Plants. Flav. & Frag. J. 8: 331-7.
Origanum vulgare Shoot *
Panax ginseng Root Essent. Oil *
Pelargonium graveolens Essential Oil *
Peumus boldus Leaf List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Pimenta dioica Leaf Essent. Oil 792400.0 1.1 *
Pimenta dioica Fruit 3500.0 36000.0 1.4 *
Pimenta dioica Flower Essent. Oil 543000.0 *
Pimenta dioica Leaf 8348.0 12000.0 0.6 *
Pimenta racemosa Leaf 16.0 21840.0 1.7 *