Chemical CARNOSOL

List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)

Activity Sort descending	Dosage	Reference
5-Lipoxygenase-Inhibitor	IC50 (uM)=2	Duke, 1992 *
Antibiotic	not available	Encarnacion Dimayuga, R., Keer Garcia, S., Halfdan Nielsen, P., and Christophersen, C. 1989. Traditional Medicine of Baja California Sur (Mexico) III. Carnosol: A Diterpene Antibiotic from Lepechinia hastata. J. Ethnopharmacology, 31: 43-48, 1991.
Antihepatotoxic	not available	Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
AntiHIV	not available	J. Nat. Prod. 56: 1426.
Antiinflammatory	not available	McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Antilipoperoxidant	not available	Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antimutagenic	not available	Economic & Medicinal Plant Research, 6: 235.
Antioxidant	not available	McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Antiradicular	not available	Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antitumor	not available	McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Antitumor-Promoter	not available	McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Cancer-Preventive	not available	Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide	not available	Encarnacion Dimayuga, R., Keer Garcia, S., Halfdan Nielsen, P., and Christophersen, C. 1989. Traditional Medicine of Baja California Sur (Mexico) III. Carnosol: A Diterpene Antibiotic from Lepechinia hastata. J. Ethnopharmacology, 31: 43-48, 1991.
Cyclooxygenase-Inhibitor	IC50 (uM) =16	Duke, 1992 *
Fungicide	not available	Encarnacion Dimayuga, R., Keer Garcia, S., Halfdan Nielsen, P., and Christophersen, C. 1989. Traditional Medicine of Baja California Sur (Mexico) III. Carnosol: A Diterpene Antibiotic from Lepechinia hastata. J. Ethnopharmacology, 31: 43-48, 1991.
Metal-Chelator	not available	McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor	not available	McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Pesticide	not available	Duke, 1992 *
Protease-Inhibitor	not available	J. Nat. Prod. 56: 1426.
Quinone-Reductase-Inducer	100 mg/kg ipr rat	Singletary, K. W. 1996. Rosemary Extract and Carnosol Stimulate Rat Liver Glutathione-s-transferase and Quinone Reductase Activities. Cancer Lett., 100: 139-144.