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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. BERBERINE

BERBERINE

Chemical ID
BERBERINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=100 mg/kg
LD50=24 mg/kg (ipr mus)
LD50=329 (orl mus)
LD50=10-20 (ivn dog)
LD50=27.5 mg/kg man
LD50=>1,000 mg/kg (orl rat)
LD50=8.2 mg/kg (ivn mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=26.4 mg/kg (ipr mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
LD50=13.2 mg/kg (scu mus) Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antisalmonella *
Antisecretory *
Antiseptic 25 ug/ml *
Antishigellic 12.5 ug/ml Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antispermigenic *
Antistaphylococcic *
Antistrep Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antisyphilitic *
Antitrachomic 0.20% *
Antitrypanosomic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antitubercular MIC=25 ug/ml *
Antitumor (brain) IC91=150 ug/ml Werbach & Murray, 1994.
Antiulcer *
Antivaginitic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiviral Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Astringent *
Bilirubinolytic *
Calcium-Antagonist Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
Candidicide *
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Mahonia repens Stem Suess, T. R. and Stermitz, F. R. 1981. The Constituents of Castilleja rhexifolia, Mahonia repens and Oncidium cebolleta. Dissertation Abstract Int B, 42: 1025-1026.
Mahonia siamensis Stem Bark 2000.0 -1.0 Ruangrungsi, N., De-Eknamkul, W., Lange, G. L. 1984. Studies on Thai Medicinal Plant. Part I. Planta Medica, 50(5): 432-433.
Menispermum canadense Plant *
Nandina domestica Plant *
Papaver somniferum Plant Father Nature's Farmacy: The aggregate of all these three-letter citations.
Phellodendron amurense Bark 8300.0 10000.0 -1.0 *
Podophyllum hexandrum Rhizome *
Podophyllum peltatum Plant *
Sanguinaria canadensis Root *
Xanthorhiza simplicissima Root 12000.0 13000.0 -0.8 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Zanthoxylum alatum Bark ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Zanthoxylum americanum Plant *
Zanthoxylum clava-herculis Plant *
Zanthoxylum clava-herculis Bark *