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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Xanthine-Oxidase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
FOLIC-ACID Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
FRAXETIN IC100=10 uM *
GALLIC-ACID IC50=24 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
GEMIN-D IC50=35 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
GERANIIN IC50=>40 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
GLISOFLAVONE IC50=>100 uM *
GLYCYCOUMARIN IC50=>100 uM *
GLYCYRRHISOFLAVANONE IC50=>100 uM *
GLYCYRRHISOFLAVONE IC50=53 uM *
HYPERIN-2''-GALLATE 73 uM *
HYPEROSIDE *
ISOQUERCETRIN-2''-GALLATE 50 uM *
ISOTERCHEBIN IC50=14 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
LICOARYLCOUMARIN IC50=>100 uM *
LICOCHALCONE-A IC50=56 uM *
LICOCHALCONE-B IC50=30 uM *
LICOCOUMARONE IC50=13 uM *
LICOPYRANOCOUMARIN IC50=>100 uM *
LUTEOLIN IC50=0.11 ug/ml Chem. & Pharm. Bull. 38: 1772.
METHYL-GALLATE IC50=29 uM Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Rhynchosia minima Burn Mouth Vine 1 0
Ribes nigrum Black Currant 4 13, 800
Ribes uva-crispa Gooseberry 2 0
Ricinus communis Castorbean 5 0
Robinia pseudoacacia Black Locust 1 70, 000
Rosa canina Rose; Dogbrier; Dog Rose 7 60, 090
Rosa centifolia Cabbage Rose 1 0
Rosa damascena Damask Rose 1 0
Rosa gallica French Rose 1 0
Rosa laevigata Cherokee Rose 1 0
Rosa multiflora Multiflora Rose 2 0
Rosa rubiginosa Rosa Mosqueta 1 26, 400
Rosa spp Rose Hips 2 26, 400
Rosmarinus officinalis Rosemary 5 0
Rubus fruticosus Blackberry 1 0
Rubus idaeus Red Raspberry; Raspberry 8 252, 500
Rubus phoenicolasius Wineberry; Wine Raspberry; Japanese Wineberry 2 0
Rubus sp. 2 0
Rumex acetosa Garden Sorrel 2 500
Rumex acetosella Sheep Sorrel 1 140, 000