An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. Quinone-Reductase-Inducer

Quinone-Reductase-Inducer

Select a Results View:

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
GLUCONASTURTIN 15 uM Tawfig,N. Heaney,R.K.,Plumb,J.A.,Fenwick,G.R.,Musk,S.R.R.,Williamson,G.1995. Dietary Glucosinolates as Blocking Agents Against Carcinogenesis: Glucosinolate Breakdown Products Assessed Induction of Quinone Reductase Activity I.Carcinogenesis 16(5)119-1194
GLUCORAPHANIN 1 uM Fahey, J. W., Zhang, Y., Talalay, P. 1997. Broccoli Sprouts: An Exceptionally Rich Source of Inducers of Enzymes that Protects Against Chemical Carcinogens. Proc. Nat. Acad. Sci., 94: 10367-10372.
IBERIN 2.4 uM Zhang, Y., Talalay, P., Cho, C. G., Posner, G. H. 1992. A Major Inducer of Anticarcinogenic Protective Enzymes from Broccoli: Isolation and Elucidation of Structure. Proc. Nat. Acad. Sci., 89: 2399-2403.
IBERVERIN 3.5 uM Zhang, Y., Talalay, P., Cho, C. G., Posner, G. H. 1992. A Major Inducer of Anticarcinogenic Protective Enzymes from Broccoli: Isolation and Elucidation of Structure. Proc. Nat. Acad. Sci., 89: 2399-2403.
INDOLE-3-CARBINOL 50 mg/kg igs mus Shertzer, H. G., Sainsbury, M. 1991. Intrinsic Acute Toxicity and Hepatic Enzyme Inducing Properties of the Chemoprotectants Indole-3-carbinol and 5,10-dihydroindeno[1,2-b]indole in... Fold Chem Toxicol, 29(4): 237-242.
IRILONE *
ISORHAMNETIN Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
JUGLONE 20 uM Duhaiman, A. S. 1996. Characterization of Zeta-Crystallin Inhibition by Juglone. Biochem. Biophys. Res. Commun., 218(3): 648-652.
KAEMPFERIDE Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
KAEMPFEROL 3 uM *
L-MAACKIAIN IC50=>13.4 uM *
LANCEOLATIN-B 22.9 uM *
LANCEOLATIN-B IC50=>76.3 uM *
LUTEIN 2.5 ug Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
MEDICARPIN IC50>74.8 uM *
MYRICETIN 36 uM Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
NEOGLUCOBRASSICIN 100 uM Fahey, J. W., Zhang, Y., Talalay, P. 1997. Broccoli Sprouts: An Exceptionally Rich Source of Inducers of Enzymes that Protects Against Chemical Carcinogens. Proc. Nat. Acad. Sci., 94: 10367-10372.
PHENETHYL-ISOTHIOCYANATE 1 uM/kg Guo, Z., et al. 1992. Effects of Phenethyl Isothiocyanate, a Carcinogenesis Inhibitor, on Xenobiotic-Metabolizing Enzymes and Nitrosamine Metabolism in Rats. Carcinogenesis, 13(12): 2205-2210.
PONGAMOL ED50=6.1 uM *
PONGAMOL IC50=18.7 uM *
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Cornus florida American Dogwood 3 0
Cornus mas Cornelian Cherry; Sorbet 4 0
Cornus officinalis Chinese Dogwood 1 0
Corylus avellana English Filbert; European Filbert; European Hazel; Hazel; Cobnut 3 0
Costus speciosus Crepe Ginger; Wild Ginger; Cane Reed 1 0
Crataegus cuneata Hawthorn 2 0
Crataegus laevigata Hawthorn; English Hawthorn; Whitethorn; Woodland Hawthorn 4 0
Crataegus monogyna Hawthorn; English Hawthorn 5 80
Crataegus rhipidophylla Hawthorn 3 0
Crocus sativus Saffron 4 0
Crotalaria juncea Sunhemp 1 0
Cryptostegia grandifolia Rubber Vine 1 0
Cucurbita pepo Pumpkin 4 0
Curcuma longa Turmeric; Indian Saffron 4 543, 580
Curcuma xanthorrhiza Javan Turmeric; Temu Lawak 1 20, 000
Curcuma zedoaria Shoti; Zedoary 1 2, 000
Cuscuta reflexa Amarbel 1 0
Cyamopsis tetragonoloba Guar; Cluster-Bean; Siam-Bean 3 0
Cycas revoluta Sago Cycas 1 0
Cymbopogon citratus West Indian Lemongrass; Lemongrass 1 0