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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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MDR-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
TAXUSPINE-B 1 ug/mL *
TAXUSPINE-C 1 ug/mL *
TAXUSPINE-D 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-F 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-G 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-H 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-J 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-K 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-L 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-M 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-O 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-P 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-Q 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-R 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-S 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-T 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
THALICARPINE 2 uM *
TOLYPORPHIN Smith, C. D., Prinsep, M. R., Caplan, F. R., Moore, R. E., Patterson, G. M. L. 1994. Reversal of Multiple Drug Resistance by Tolyporphin, a Novel Cyanobacterial Natural Product. Oncol. Res., 6: 211-218.
TOLYPORPHIN-A 0.5 ug/ml Prinsep, M. R., Patterson, G. M. L., Larsen, L. K., Smith, C. D. 1995. Further Tolyporphins From the Blu-Green Alga Tolypothrix nodosa. Tetrahedron, 51(38): 10523-10530.
TOLYPORPHIN-B 0.5 ug/ml Prinsep, M. R., Patterson, G. M. L., Larsen, L. K., Smith, C. D. 1995. Further Tolyporphins From the Blu-Green Alga Tolypothrix nodosa. Tetrahedron, 51(38): 10523-10530.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Chamaecytisus eriocarpus 1 0
Chamaecytisus hirsutus 1 0
Chamaecytisus ratisbonensis 1 0
Chamaecytisus smyrnaeus 1 0
Chamaecytisus supinus 1 0
Chamaespartium sagittale 1 0
Chamaespartium tridentatum 1 0
Chronanthus biflorus 1 0
Cicer arietinum Chickpea; Garbanzo 1 92.19999694824219
Cinchona officinalis Lojabark; Quinine 3 0
Cinchona pubescens Quinine; Red Cinchona; Red Peruvian-Bark; Redbark 2 316, 644
Cinchona spp Quinine 3 280, 000
Citrus aurantium Petitgrain; Bitter Orange 1 0
Citrus limon Lemon 2 5
Citrus reticulata Mandarin; Tangerine 2 2, 428.39990234375
Citrus sinensis Orange 2 0
Citrus spp Citrus 1 0
Clitoria falcata 1 0
Clitoria ternatea 1 25
Colchicum autumnale Autumn Crocus; Meadow Saffron 1 0