An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. MDR-Inhibitor

MDR-Inhibitor

Select a Results View:

Download these results as:
CSV
EXCEL
PDF
List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
TAXUSPINE-B 1 ug/mL *
TAXUSPINE-C 1 ug/mL *
TAXUSPINE-D 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-F 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-G 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-H 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-J 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-K 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-L 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-M 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-O 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-P 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-Q 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-R 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-S 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
TAXUSPINE-T 1 ug/mL Kobayashi, J., et al. 1997. Effects of Taxoids From Taxus cuspidata on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells. Bioorg. Med. Chem. Lett., 7: 393-398.
THALICARPINE 2 uM *
TOLYPORPHIN Smith, C. D., Prinsep, M. R., Caplan, F. R., Moore, R. E., Patterson, G. M. L. 1994. Reversal of Multiple Drug Resistance by Tolyporphin, a Novel Cyanobacterial Natural Product. Oncol. Res., 6: 211-218.
TOLYPORPHIN-A 0.5 ug/ml Prinsep, M. R., Patterson, G. M. L., Larsen, L. K., Smith, C. D. 1995. Further Tolyporphins From the Blu-Green Alga Tolypothrix nodosa. Tetrahedron, 51(38): 10523-10530.
TOLYPORPHIN-B 0.5 ug/ml Prinsep, M. R., Patterson, G. M. L., Larsen, L. K., Smith, C. D. 1995. Further Tolyporphins From the Blu-Green Alga Tolypothrix nodosa. Tetrahedron, 51(38): 10523-10530.
Download these results as:
CSV
EXCEL
PDF
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Macroptylium martii 1 0
Macrotyloma axillare 1 0
Macrotyloma uniflora 1 0
Mahonia repens Creeping Barberry; Oregon Barberry; Oregon Grape-Holly; Oregon Grape 1 0
Medicago sativa Alfalfa; Lucerne 1 0
Mentha longifolia Biblical Mint 1 0
Mentha pulegium European Pennyroyal 1 0
Mentha spicata Spearmint; Hortela da Folha Miuda 1 0
Moghania macrophylla 1 0
Mucuna deeringiana 1 0
Mucuna pruriens Cowage; Velvetbean 1 28
Neonotonia wightii 1 4.989999771118164
Olea europaea Olive 1 0
Ononis spinosa Spiny Restharrow; Restharrow; Hauhechel (Ger.) 1 114
Panax ginseng Chinese Ginseng; Oriental Ginseng; Ginseng; Korean Ginseng 8 5, 732, 630
Panax japonicus Japanese Ginseng 2 6, 700
Panax notoginseng Sanchi Ginseng 5 0
Panax quinquefolius American Ginseng; Ginseng 8 244, 882
Pausinystalia johimbe Yohimbe 1 0
Pericopsis laxiflora 1 0