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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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COX-2-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PTEROSTILBENE IC50=84 uM *
PUNICIC-ACID *
QUERCETIN <40 uM *
RESVERATROL >2.5->22.5 uM *
RESVERATROL 50 uM/ *
RESVERATROL 30 uM/ Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
ROSMARINIC-ACID IC>58=1,000 uM *
RUTAECARPINE 2.5 ug/ml (strong activity) Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
SALICYLIC-ACID Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
TRANS-RESVERATROL 20 uM/ Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
UROLITHIN-A *
URSOLIC-ACID IC50=130 uM/ *
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Echinacea purpurea Echinacea; Eastern Purple-Coneflower; Purple-Coneflower 2 6.6000001430511475
Echinacea spp Coneflower; Echinacea 5 4.400000095367432
Elaeagnus angustifolia Russian Olive; Silver Berry 4 8, 560
Elaeagnus commutata Silver Berry 1 1.399999976158142
Elaeagnus pungens Thorny Silver Berry 2 0
Elaeagnus umbellatus Russian Olive 1 30
Elaeis guineensis African Oil Palm 1 575
Eleocharis dulcis Water chestnut 1 0
Elettaria cardamomum Cardamom 2 2
Eleutherococcus senticosus Eleuthero Ginseng; Siberian Ginseng; Spiny Ginseng; Wu jia; Ci wu jia (Pinyin) 3 990
Elsholtzia blanda Bantaluki; Bantulsi 1 3.5999999046325684
Ephedra sinica Ma Huang; Chinese Ephedra 4 90
Equisetum arvense Field Horsetail; Horsetail 5 16, 098
Equisetum hyemale Horsetail; Scouring Rush 1 0
Eriobotrya japonica Loquat 6 1, 023.5999755859375
Eriodictyon californicum Yerba Santa; California Yerba Santa; Hierba Santa; Mountain Balm; Bear's Weed; Consumptive's Weed; Tarweed; Gum Bush; Holy Herb 2 1, 818
Eryngium foetidum Culantro; Cilantro; False Coriander; Shadow-Beni; Stinkweed; Stinkdistel (Ger.) 1 300
Erythrina berteroana Pito 1 14
Erythrina fusca Coral Bean; Gallito 1 250
Erythroxylum coca Coca 3 7