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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antiplasmodial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
15-DESACETYLUNDULATONE IC50=0.047 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
16-EPIAFFININE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
17-METHOXY-28-NORISOIGUESTERIN IC50=0.028-0.37 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
18-HYDROXYISOSUNGUCINE IC50=0.1-0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
18-HYDROXYSUNGUCINE IC50=1-4 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
2-(2,4-DIHYDROXYPHENYL)-5,6-METHYLENEDIOXYBENZOFURAN EC50=27 ug/ml Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147.
20-EPIANTIRHINE IC50=7.5 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
28-NOR-IGOIGUESTERIN-17-CARBALDEHYDE IC50=0.080-0.094 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3,4,5-TRIMETHOXYPHENYL(6'-O-GALLOYL)-O->D-GLUCOPYRANOSIDE IC50=3 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-HYDROXY-6'-DESMETHYL-9-O-METHYL-THALIFABORAMINE IC50=0.05-0.24 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-HYDROXY-THALIFABORAMINE IC50=0.01-0.18 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-METHOXYSAMPANGINE IC50=0.09-0.28 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-METHYLNAPHTHARAZIN IC50=5.8 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
3-O-BENZOYLHOSLOPPONE IC50=0.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
5,7-DIMETHOXY-8-(3'-HYDROXY-3'-METHYL-1'-BUTENE) IC50=8.8-16.25 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6'-DESMETHYL-THALIFABORAMINE IC50=0.01-0.15 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ACETYLSWIETENOLIDE IC50=7.5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
6-ALPHA-TIGLOYLOXYGLAUCARUBOL IC50=0.257 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-DEACETYLKHIVORIN IC50=5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
7-EPIDIONCHOPHYLLINE-A IC50=0.2 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Punica granatum Pomegranate; Grenadier (Fr.); Granatapfelbaum (Ger.); Granatapfelstrauch (Ger.); Zakuro (Jap.); Romanzeiro (Port.); Granado (Sp.); Mangrano (Sp.) 6 134, 400
Putoria calabrica 1 0
Pygeum acuminatum 1 0
Pyrus communis Pear 2 28
Quercus alba White Oak 1 0
Quercus bambusaefolia 1 3.700000047683716
Quercus championi 1 3.299999952316284
Quercus infectoria Aleppo Oak; Dyer's Oak; Gall Oak 2 0
Quercus myrsinaefolia 1 1.100000023841858
Quercus robur English Oak 1 0
Quercus rubra Northern Red Oak 1 0
Quercus suber Cork Oak 1 0
Quercus velutina Black Oak 1 0
Quisqualis indica Rangoon Creeper 1 0
Rauvolfia serpentina Indian Snakeroot; Serpentine Wood 1 0
Rauvolfia tetraphylla Four-Leaf Devilpepper; Pinque-Pinque 1 0
Rauvolfia vomitoria African Snakeroot 1 0
Rhododendron arboreum 1 0
Rhododendron dauricum Chinese Alpenrose 2 0
Rhododendron falconeri 1 0